Biochemical Studies in Experimentally Induced-hyperthyroid Rats Treated with Folic and Ascorbic Acid

Tarek M Mohamed¹, Ehab Tousson^2, , Doha M. Beltagy³ and Ahmed Samy El Said¹

¹Biochemistry Unit, Chemistry Department, Faculty of Science, Tanta University, Egypt

²Department of Zoology, Department of Chemistry, Faculty of Science, Tanta University, Egypt

³Department of Chemistry, Faculty of Science, Damanhour University, Egypt

Cite this paper:
Tarek M Mohamed, Ehab Tousson, Doha M. Beltagy and Ahmed Samy El Said. Biochemical Studies in Experimentally Induced-hyperthyroid Rats Treated with Folic and Ascorbic Acid. Biomedicine and Biotechnology. 2014; 2(4):60-65. doi: 10.12691/bb-2-4-1

Abstract

Hyperthyroidism is a relatively prevalent condition, and is one of the most common endocrine problems seen in clinical practice, high serum cholesterol and increased oxidative stress are common associated risk factors of hyperthyroidism. Multivitamin deficiencies in folate and vitamin C are also one of the hyperthyroidism complications. Individually or combined Folic acid and vitamin C were introduced to hyperthyroid induced rats. A relative enhancement in the thyroid hormones with a normal lipid profile was noticed. Previous researches confirmed that the depletion on the lipid in hyperthyroidism will be gained after treatment.

Keywords:
Hyperthyroidism lipid profile cortisol oxidative stress folic acid vitamin C

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