Biomedicine and Biotechnology
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Biomedicine and Biotechnology. 2025, 10(1), 1-10
DOI: 10.12691/bb-10-1-1
Open AccessArticle

Application of Biotechnology for Food Production and Quality Improvement in the View of Food Security Aspect

Mahendra Pal1, , Ravindra Zende2, Tesfaye Rebuma3, Alemayehu Bekele4, Aishwarya Nair2 and Dhwani Upadhyay5

1Narayan Consultancy of Veterinary Public Health, and Microbiology, B-103, Sapphire Lifestyle, Bharuch, Gujarat, India

2Department of Veterinary Public Health, Mumbai Veterinary College, Parel, Mumbai, India

3Shaggar City Administration Sebeta Sub-City Agricultural Office, Sebeta, Oromia, Ethiopia

4Wallaga University School of Veterinary Medicine Department of Clinical Studies, Wallaga, Nekemte, Oromia Region, Ethiopia

5Department of Life Sciences, School of Sciences, GSFC University, Vadodara, Gujarat, India

Pub. Date: May 27, 2025

Cite this paper:
Mahendra Pal, Ravindra Zende, Tesfaye Rebuma, Alemayehu Bekele, Aishwarya Nair and Dhwani Upadhyay. Application of Biotechnology for Food Production and Quality Improvement in the View of Food Security Aspect. Biomedicine and Biotechnology. 2025; 10(1):1-10. doi: 10.12691/bb-10-1-1

Abstract

With the global population rapidly increasing and cultivable land remaining limited, a significant portion of the world’s population continues to suffer from undernourishment. Addressing this issue necessitates the exploration and adoption of all available alternatives under current global conditions. In this context, modern biotechnology has emerged as a vital complementary tool to traditional agricultural practices, offering potential solutions to challenges related to food insecurity. Biotechnology involves the use of biological systems, living organisms, or their components to develop or modify products and processes for specific applications. It encompasses a wide range of techniques, from age-old practices, such as brewing wine and fermenting cheese, to advanced methods involving the genetic manipulation of plants, animals, and microorganisms. Agricultural biotechnology can be broadly categorized into two main approaches. The former enhances conventional breeding by utilising genetic information to accelerate and improve selection. The second involves direct genetic modification to create new organisms with desired traits. This latter method has led to the development and commercialisation of Genetically Modified Organisms (GMOs), which often exhibit characteristics not naturally found within a species. Globally, the most widely cultivated GMOs include soybean, maize, and cotton, which are primarily engineered for improved agronomic traits such as pest resistance and herbicide tolerance. These traits are expected to remain central to the future development of GM crops. In addition to crops, transgenic animals, such as fast-growing salmon and genetically modified cattle, with enhanced protein production are in the advanced stages of research, while many other genetically engineered animals for food purposes are still undergoing early research and development. Genetically modified microorganisms are extensively used in the production of enzymes and other processing aids in a broad array of processed foods. Therefore, biotechnology has the potential to optimise food production and distribution systems, aligning them with the nutritional demands of a growing global population. Its strategic application can strengthen food supply chains and ensure stable, affordable, and sustainable access to safe and nutritious food on both regional and global scales. Additionally, integrating biotechnology with nutritional education, especially for vulnerable populations, can contribute to global food security and public health.

Keywords:
Biotechnology Food security Genetically modified organisms Public health Technologies

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References:

[1]  WHO (World Health Organization). Global prevalence of vitamin A deficiency in populations at risk 1995–2005. WHO Global Database on Vitamin A Deficiency, 2009. [Available at: http:// whqlibdoc.who.int/ publications/2009/9789241598019eng.pdf].
 
[2]  Persely L., Lai L.X., Kang J.X., Li R.F., Wang J.D., Witt W.T., Yong H.Y., Hao Y.H., Wax D.M., Murphy C.N., Rieke A., Samuel M., Linville M.L., Korte S.W., Evans R.W., Starzl T.E., Prather R.S., Dai Y.F., Generation of cloned transgenic pigs rich in omega-3 fatty acids. Nature Biotechnology, 24:435–436, 2000.
 
[3]  Clive J., Gupta K., Safe use of biotechnology. In: Persley G.J. (Ed.), Biotechnology for Developing Country Agriculture: Problems and Opportunities: 2020 Vision, Focus 2, Brief 6 of 10, 2010.
 
[4]  Cohen J.I., Managing agricultural biotechnology: Addressing research program needs and policy implications, Wallingford, UK, 2009.
 
[5]  Conway G., Ruttan V., The doubly green revolution: Food for all in the 21st Century. Penguin Books, London, 1999.
 
[6]  Dyson T., World food trends and prospects to 2025. Proceedings of the National Academy of Sciences, 96: 5929–5936, 2009.
 
[7]  Pal A., Chakravarty A.K., Disease resistance for different livestock species. Genetics and Breeding for Disease Resistance of Livestock, 2020: 271–296, 2020.
 
[8]  Beyers L., Ismaël Y., Piesse J., Thirtle C., Can GM-technologies help the poor? The efficiency of Bt cotton adopters in the Makhathini Flats of Kwazulu-Natal. ISNAR Consultation on Biotechnology and Rural Livelihood, The Hague, 2001.
 
[9]  CEC (Commission of the Communities), Economic impacts of genetically modified crops on the agrifood sector: A first review. Working Document Rev. 2, Directorate General for Agriculture, 2002.
 
[10]  FAO/WHO (Food and Agriculture Organization/World Health Organization). Evaluation of data on ractopamine residues in pig tissues. Joint FAO/WHO Expert Committee on Food Additives (JECFA). Meeting Report, 2001. [Available at: www. fao.org/ docrep/012/i1618e/i1618e00.pdf.
 
[11]  Adato M., Meinzen R., Dick R., Assessing the impact of agricultural research on poverty using the Sustainable Livelihoods Framework. International Food Policy Research Institute Discussion Paper, 89 or 128, 2009.
 
[12]  Clark E.A., Factoring in the Environment for Decisions on Biotechnology in Agricultural Production. NAEC Workshop Presentation, Ottawa, Canada, 2008.
 
[13]  Thompson E., Echelard Y., Ziomek C.A., Meade H.M., Production of recombinant therapeutic proteins in the milk of transgenic animals. Biopharm International, 19:36–40, 2003.
 
[14]  USDA (U.S. Department of Agriculture), APHIS (Animal and Plant Health Inspection Service), Petition for determination of non-regulated status: Arctic™ Apple (Malus × domestica), Events GD743, and GS784. USDA-APHIS Report, 2012. [Available at: http:// www.aphis.usda.gov/ brs/aphisdocs/1016101p.pdf].
 
[15]  NRC (National Research Council). Impact of genetically engineered crops on farm sustainability in the United States. National Academies Press, Washington, DC, 2010. [Available at: http://dels.nas.edu/ resources/static-assets/ materials‐based‐on‐reports/reports‐in-brief/ genetically-engineered -crops-report-brief-final.pdf].
 
[16]  FDA (Food and Drug Administration), Questions and Answers on Food from Genetically Engineered Plants. FDA Food Biotechnology, 2013. [Available at: http:// www.fda.gov/ Food/ FoodScienceResearch/ Biotechnology/ucm346030.htm].
 
[17]  UNF., FAO/WHO., Modern Biotechnology and Human Health and Development: an evidence‐based study. UN/WHO Report, 2012.
 
[18]  Lillico S.G., Sherman A., McGrew M.J., Robertson C.D., Smith J., Haslam C., Barnard P., Radcliffe P.A., Mitrophanous K.A., Elliot E.A., Sang H.M., Oviduct-specific expression of two therapeutic proteins in transgenic hens. Proceedings of the National Academy of Sciences of the United States of America, 104: 1771–1776, 2007.
 
[19]  NRC (National Research Council), Animal biotechnology: Science-based concerns. National Academies Press, Washington, D.C, 2002.
 
[20]  Shakweer W.M.E., Krivoruchko A.Y., Dessouki S.M., Khattab A.A., A review of transgenic animal techniques and their applications. Journal of Genetic Engineering and Biotechnology, 21(1): 55, 2023.
 
[21]  FDA (Food and Drug Administration), Regulation of genetically engineered animals. FDA Consumer Updates, 2012. [Available at: http:// www.fda.gov/ ForConsumers/ ConsumerUpdates/ ucm048106.htm].
 
[22]  FDA (Food and Drug Administration), Animal cloning. FDA Safety and Health, 2008. [Available at: .http:// www.fda.gov/ AnimalVeterinary/ SafetyHealth/ AnimalCloning/default.htm].
 
[23]  Edgerton M.D., Increasing crop productivity to meet global needs for feed, food, and fuel. Plant Physiology, 149 (1):7–13, 2009.
 
[24]  Peng J., Richards D.E., Hartley N.M., Murphy G.P., Devos K.M., Flintham J.E., Beales J., Fish L.J., Worland A.J., Pelica F., Sudhakar D., Christou P., Snape J.W., Gale M.D., Harberd N.P., ‘Green revolution’ genes encode mutant gibberellin response modulators. Nature, 400:256–261, 2009.
 
[25]  Juma C., Gupta A., Safe use of biotechnology. In: Persley G.J. (Ed.), Biotechnology for Developing Country Agriculture: Problems and Opportunities, 2020 Vision, Focus 2, Brief 6 of 10, International Food Policy Research Institute, Washington DC, USA, 2010.
 
[26]  Sharma K.K., Lavanya M., Recent developments in transgenics for abiotic stress in legumes of the semi-arid tropics. In: Ivanaga M. (Ed.), Genetic Engineering of Crop Plants for Abiotic Stress, JIRCAS Working Report, 23:61–73, 2002.
 
[27]  Smart C., Thomas H., Hosken S., Schuch W.W., Drake C.R., Grierson D., Farrell A., John A., Greaves J.I., Regulation of senescence. Patent Application EP, 719341, 2006.
 
[28]  James C., Smart H., Thomas S., Hosken W.W., Schuch C.R., Drake D., Grierson A., Farrell I., John J.A., Greaves J., Regulation of senescence. Patent Application EP, 719341, 2004.
 
[29]  Potrykus D.E., Richards N.M., Hartley G.P., Murphy K.M., Devos J.E., Flintham J., Beales L.J., Fish A.J., Worland F., Pelica D., Sudhakar P., Christou J.W., Snape M.D., Gale N.P., Harberd N.P., ‘Green revolution’ genes encode mutant gibberellin response modulators. Nature, 400: 256–261, 1999.
 
[30]  World Health Organization (WHO) and United Nations Children’s Fund (UNICEF). (2005). Genetically Modified Foods and Their Impact on Global Food Security. WHO/ UNICEF Report.
 
[31]  Schmitdt R.R., Kasinathan P., Hamir A.N., Castilla J., Sathiyaseelan T., Vargas F., Sathiyaseelan J., Wu H., Matsushita H., Koster J., Kato S., Ishida I., Soto C., Robl J.M., Kuroiwa Y., Production of cattle lacking prion protein. Nature Biotechnology, 25: 132–138, 2007.
 
[32]  FAO/WHO (Food and Agriculture Organization/World Health Organization), Evaluation of data on ractopamine residues in pig tissues. Joint FAO/WHO Expert Committee on Food Additives (JECFA), Meeting Report, 2003. [Available at: www.fao.org/ docrep/012/i1618e/ i1618e00.pdf].
 
[33]  Potrykus J.T., Cook M.A., McNiven G.F., Richardson A.M., Sutterlin A.M., Growth rate, body composition and feed digestibility/conversion of growth-enhanced transgenic Atlantic salmon (Salmo salar). Aquaculture, 188: 15–32, 2000.
 
[34]  Lehrer S.B., Bannon G.A., Risks of allergic reactions to biotech proteins in foods: Perception and reality. Allergy, 60(5): 559–564, 2005.
 
[35]  Newell M.C., Barry M., Nutritionally improved agricultural crops. Plant Physiology, 147: 939–953, 2008.
 
[36]  Crawford A.W., Wang C., Jenkins D.J., Lemke S.L., Estimated effect on fatty acid intake of substituting a low‐saturated, high‐oleic, low‐linolenic soybean oil for liquid oils. Nutrition Today, 46 (4): 189‐196, 2011.
 
[37]  TIHGMC (The International Human Genome Mapping Consortium), A physical map of the human genome. Nature, 409:934–941, 2001.
 
[38]  IFT (Institute of Food Technologists), Antimicrobial Resistance: Implications for the Food System. Comprehensive Reviews in Food Science and Food Safety, 5 (3): 71–137, 2006.
 
[39]  FDA (Food and Drug Administration), Genetically engineered animals. Development Approval Process, 2012 b [Available at: http://www.fda.gov/ AnimalVeterinary/ DevelopmentApprovalProcess/ GeneticEngineering/ GeneticallyEngineeredAnimals/default.htm].
 
[40]  Du S.J., Gong Z., Fletcher G.L., Shears M.A., King M.J., Idler D.R., Hew C.L., Growth enhancement in transgenic Atlantic salmon by the use of an "all fish" chimeric growth hormone gene construct. Nature Biotechnology, 10: 176–181, 2002.
 
[41]  Das S, Ray MK, Panday D, Mishra PK. Role of biotechnology in creating sustainable agriculture. PLOS Sustainability and Transformation, 13; 2 (7): 2021.
 
[42]  Martínez A, Abanto M, Días NB, Olate P, Pérez Nuñez I, Díaz R, Sepúlveda N, Paz EA, Quiñones J. Recent Trends in Food Quality and Authentication: The Role of Omics Technologies in Dairy and Meat Production. International Journal of Molecular Sciences, 6; 26(9): 4405, 2025.
 
[43]  Capper J.L., Castañeda‐Gutiérrez E., Cady R.A., Bauman D.E., The environmental impact of recombinant bovine somatotropin (rbST) use in dairy production. Proceedings of the National Academy of Sciences (PNAS), 105(28): 9668‐9673, 2008.
 
[44]  Maeda I., Genetic modification in Bacillus subtilis for production of C30 carotenoids. Methods in Molecular Biology (Clifton, N.J.), 892: 197–205, 2012.
 
[45]  Imran M, Tausif MA, Waseem M. Effect of Bovine Somatotropin Administration on Mastitis Incidence and Body Condition Score in Dairy Buffaloes. Insights in Animal Science, 1(2): 18-24, 2024.
 
[46]  Vickram AS, Shofia SI, Palanivelu J, Karishma S, Yaashikaa PR. A comprehensive analysis and exploration of the recent developments in the utilization of genetically modified microorganisms for the remediation of hazardous dye pollutants. Groundwater for Sustainable Development, 13: 101315, 2024.
 
[47]  Pal M, Patel AS, Bariya AR, Godishala V, Kandi V. A review of biotechnological applications in food processing of animal origin. Am J Food Sci Technol, 5(4): 143–8, 2017.