American Journal of Sports Science and Medicine
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American Journal of Sports Science and Medicine. 2013, 1(3), 42-46
DOI: 10.12691/ajssm-1-3-3
Open AccessReview Article

Overview of Lactate Metabolism and the Implications for Athletes

Aldeam Facey1, , Rachael Irving1 and Lowell Dilworth2

1Department of Basic Medical Sciences, Biochemistry Section the University of the West Indies Mona Campus

2Department of Pathology, the University of the West Indies Mona Campus

Pub. Date: September 21, 2013

Cite this paper:
Aldeam Facey, Rachael Irving and Lowell Dilworth. Overview of Lactate Metabolism and the Implications for Athletes. American Journal of Sports Science and Medicine. 2013; 1(3):42-46. doi: 10.12691/ajssm-1-3-3


Lactate metabolism is an integral pathway in physical exercise. Numerous contrasting views exist regarding the physiological effects of lactate and its roles post production. This paper attempts to clarify and highlight the significance of lactate in exercise. Lactate production is associated with muscular fatigue; and is a major limitation in athletic performance. This fatigue is partially due to the production of H+ ions which depresses muscle functions. Lactate is transported in the skeletal muscles through plasma monocarboxylate transport (MCT) system and is utilized by muscles such as the heart and red muscles. It is also very important that the lactate produced to satisfy high energy demands is cleared from the muscles and metabolized by the liver or be utilized as an energy substrate. There is a marked positive correlation existing between adiposity and lactate production. Numerous physiological properties inclusive of adiposity, VO2 max, lactate threshold and insulin sensitivity affect and regulate lactate production.

hypoxia lactate adiposity VO2 max metabolism athletes

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