The Role of Mollucas Traditional Food on the Improvement of Risk Factors of Coronary Heart Disease

Yusuf Huningkor¹, Suryani As’ad², Peter Kabo³ and Gatot S. Lawrence.^4,

¹Department of Internal Medicine, Faculty of Medicine, Pattimura University – Dr.Haulussy Hospital, Ambon, Indonesia

²Department of Clinical Nutrition, Faculty of Medicine and Postgraduate Medicine- Dr.Wahidin Sudirohusodo Hospital-Hasanuddin University Hospital (HUH), Hasanuddin University, Makassar, Indonesia

³Department of Cardiology and Clinical Pharmacology, Faculty of Medicine, Hasanuddin University - Dr.Wahidin Sudirohusodo Hospital-Hasanuddin University Hospital (HUH), Makassar, Indonesia

⁴Vascular Research Unit, Department of Pathology and amily Medicine, Faculty of Medicine, Hasanuddin University – Dr.Wahidin Sudirohusodo Hospital-Hasanuddin University Hospital (HUH), Makassar, Indonesia

Cite this paper:
Yusuf Huningkor, Suryani As’ad, Peter Kabo and Gatot S. Lawrence.. The Role of Mollucas Traditional Food on the Improvement of Risk Factors of Coronary Heart Disease. American Journal of Medical Sciences and Medicine. 2015; 3(1):4-7. doi: 10.12691/ajmsm-3-1-2

Abstract

Background: More than 60% of the global burden of coronary heart disease occurs in developing countries and approximately 75% of cardiovascular disease can be attributed to conventional risk factors, most of which is modifiable. The Indonesia Diabetes-Obesity-Cardiovascular disease (DOCAR) Prevent Study has started from 2005 focusing on finding ways with local wisdom in preventing DOCAR. Purpose: The purpose of this study is to examine the association between the Mollucas Traditional Food (MTF) diet and the risk factors of CHD. Methods: The design of the study is cross sectional. All participants were only men, pure mollucas ethnic, age ranging from 40 to 60 years old. The participants were devided into two group; 73 were in Ambon city with Non-MTF diet and 73 in Taniwel Village, West Seram district with MTF diet. Data were collected through measurements of physical and laboratory parameters (Lipid profile, adiponectin, free fatty acid [FFA], oxLDL, hsCRP) and analysed using univariat, independent - sample T-test, linier regression and double linier regression methods. Results: The CHD risk factors in non-MTF compare to MTF diet group are: waist circumference are 93.35 ±9.57 and 78.84±7.8 cm respectively (p=0.000); adiponectin level are 5.53±2.83 ng/mL and 12.06 ± 4.64 ng/mL respectively (p=0.000); hs-CRP level are 4.52 ± 9.69 mg/L and 3.61 ± 6.37 mg/L respectively (p=0.507); FFA level are 0.43 ± 0.24 mM and 0.37 ±0.47 mM respectively (p=0.379); Ox-LDL level are 66.14 ± 31.11 ug/mL and 66.09 ± 27.55 ug/mL respectively (p=0.991). The correlation analisis revealed that food consumption i.e. non-MTF and MTF have significant impact on waist circumference (r=0,642, p=0.000) and adiponectin (r=0.649, p=0.000); but not with hsCRP (r=0.003; p-0.97), free fatty acids (r=0.073, p=0.379), as well as oxidized LDL (r=0.001, p=0.991). Conclusion: These results might indicate that Mollucas Traditional Food (MTF) provide better protective value than non-MTF through adiponectin level and body weight instead of inflammation (hsCRP) and lipid (FFA and oxLDL) mechanisms.

Keywords:
mollucas traditional food coronary heart disease risk factor obesity waist circumference adiponectin hs-CRP free fatty acid Ox-LDL

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