American Journal of Medical Sciences and Medicine
ISSN (Print): 2327-6681 ISSN (Online): 2327-6657 Website: https://www.sciepub.com/journal/ajmsm Editor-in-chief: Apply for this position
Open Access
Journal Browser
Go
American Journal of Medical Sciences and Medicine. 2014, 2(2), 48-53
DOI: 10.12691/ajmsm-2-2-5
Open AccessReview Article

Hypertension and Autonomic Control

Natália Turri da Silva1, , Thais Roque Giacon1, Franciele Marques Vanderlei1, Ana Laura Ricci Vitor1, Carlos Marcelo Pastre1 and Luiz Carlos Marques Vanderlei1

1Physiotherapy Department, Faculdade de Ciências e Tecnologia da UNESP – FCT/UNESP, Presidente Prudente, Brazil

Pub. Date: April 28, 2014

Cite this paper:
Natália Turri da Silva, Thais Roque Giacon, Franciele Marques Vanderlei, Ana Laura Ricci Vitor, Carlos Marcelo Pastre and Luiz Carlos Marques Vanderlei. Hypertension and Autonomic Control. American Journal of Medical Sciences and Medicine. 2014; 2(2):48-53. doi: 10.12691/ajmsm-2-2-5

Abstract

Arterial hypertension is considered one of the most important public health problems and had their development, progression and complications associated with the autonomic nervous system (ANS). In this context, the present systematic review aim at gathering recent studies (2003-2013) that addressed the relation between ANS and hypertension, in order to update the knowledge in the last 10 years. Searches were made onMedLine / PubMed, PEDro, SciELO, IBECS, COCHRAINE and LILACS databases using the intersection between the keywords "hypertension", "autonomic nervous system", "sympathetic nervous system ", "parasympathetic nervous system " and "heart rate variability”. A total of 17 articles were included and main findings of this review indicating the acute influence of the ANS in different types of hypertension characterized by a reduction of the overall heart rate variability (HRV) and a reduction in the parasympathetic component of ANS evaluated by linear indexes. In addition, the behavior of the sympathetic component could present an increase or a reduction according to the study design. Thus further studies to assess the influence of chronic influence of ANS on hypertension as well as investigations by nonlinear HRV indexes are needed.

Keywords:
hypertension autonomic nervous system sympathetic nervous system parasympathetic nervous system

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References:

[1]  Ferreira JS, Aydos RD. “Prevalência da hipertensão arterial emcrianças e adolescentes obesos”. Ciência& Saúde Coletiva.2010; 15(1): 97-104.
 
[2]  Sociedade Brasileira de Cardiologia / Sociedade Brasileira de Hipertensão / Sociedade Brasileira de Nefrologia. “VI Diretrizes Brasileiras de Hipertensão”. ArqBrasCardiol 2010; 95(1 supl.1): 1-51.
 
[3]  Passos VMA, Assis TD, Barreto SM. “Hipertensão arterial no Brasil: estimativa de prevalência a partir de estudos de base populacional.” Epidemiologia e Serviços de Saúde. 2006; 15(1): 35-45.
 
[4]  Rabetti AC, Freitas SFT. “Avaliação das ações em hipertensão arterial sistêmica na atenção básica”. Rev Saúde Pública. 2011; 45(2): 258-68.
 
[5]  Costa JMBS, Silva MRF, Carvalho EF. “Avaliação da implantação da atenção à hipertensão arterial pelas equipes de Saúde da Família do município do Recife (PE, Brasil)”. Ciência & Saúde Coletiva. 2011; 16(2): 623-633.
 
[6]  Schmidt MI, Duncan BB, Hoffmann JF, Moura L, Malta DC, Carvalho RMSV. “Prevalência de diabetes e hipertensão no Brasil baseada em inquérito de morbidadeauto-referida”, Brasil, 2006. Rev Saúde Pública.2009; 43(Supl 2): 74-82.
 
[7]  Nogueira D, Faerstein E, Coeli CM, Chor D, Lopes CS, Werneck GL. “Reconhecimento, tratamento e controle da hipertensão arterial: Estudo Pró-Saúde, Brasil.” Rev Panam Salud Publica. 2010; 27(2): 103-9.
 
[8]  Pontes, Fernanda Costa da Cruz de. Investigação de marcadores periféricos alternativos da hiperatividade simpática central em modelo experimental de hipertensão arterial / Fernanda Costa da Cruz Pontes. – Rio de Janeiro, 2012. iv, 48 f. il. ; 30 cm. Dissertação (Mestrado em Biologia Celular e Molecular) - Fundação Oswaldo Cruz. Rio de Janeiro, RJ, 2012.
 
[9]  Hering D, Narkiewicz K. “Sympathetic nervous system and arterial hypertension: new perspectives, new data.” Kardiologia Polska 2013; 71(5):441446.
 
[10]  Jiang W, Zhang XZ, Gu ML. “Involvement of sympathetic nervous system in the pathogenesis of hypertension”. ChineseJournalof Medical Genetics. 2013; 30(5): 565-9.
 
[11]  Pinheiro CHJ, Medeiros RAB, Pinheiro DGM, Marinho MJF. “Modificação do padrão respiratório melhora o controle cardiovascular na hipertensão essencial.” ArqBrasCardiol. 2007; 88(6): 651-659.
 
[12]  Neta NMA, Gomes MAM, Kanashiro CA, Miranda CC, Paiva AMG, Sampaio DL, Aragão LG. “Análise do índice de amplificação sistólico em pacientes acima de 55 anos utilizando atenolol associado ou não a diurético.” Rev Bras Cardiol. 2012; 25(1): 35-40.
 
[13]  Task Force of the European Society of Cardiology and the North American society of pacing and electrophysiology. “Heart rate variability: standards of measurement, physiological interpretation and clinical use”. Circulation. 1996; 93: 1043-65.
 
[14]  Cambri LT, Fronchetti L, De-Oliveita F., Gevaerd MS. “Variabilidade da freqüência cardíaca e controle metabólico”. ArqSannyPesq Saúde. 2008; 1(1): 72-82.
 
[15]  Vanderlei LCM, Pastre CM, Hoshi RA, Carvalho TD, Godoy MF. “Noções básicas de variabilidade da frequência cardíaca e sua Aplicabilidade Clínica”. RevBrasCirCardiovasc. 2009; 24(2): 205-217.
 
[16]  Virtanen R, Jula A, Kuusela T, Helenius H e Voipio-Pulkki LM. “Reduced heart rate variability in hypertension: associations with lifestyle factors and plasma renin activity.” Journal of Human Hypertension. 2003; 17: 171-179.
 
[17]  Neumann SA, Jennings JR, Muldoon MF, Manuck SB. “White-coat hypertension and autonomic nervous system dysregulation.” AJH. 2005; 18: 584-588.
 
[18]  Prakash E Sankaranarayanan, Madanmohan, Sethuraman KR, Narayan SK. “Cardiovascular autonomic regulation in subjects with normal blood pressure, high-normal blood pressure and recent-onset hypertension.” Clinical and Experimental Pharmacology and Physiology. 2005; 32: 488-494
 
[19]  Schroeder EB, Liao D, Chambless LE, Prineas RJ, Evans GW, Heiss G. “Hypertension, blood pressure, and heart rate variability. The Atherosclerosis risk in communities (ARIC) study”. Hypertension. 2003; 42: 1106-1111.
 
[20]  Ruediger H, Seibt R, Scheuch K, Krause M eAlam S. “Sympathetic and parasympathetic activation in heart rate variability in male hypertensive patients under mental stress”. Journal of Human Hypertension. 2004; 18: 307-315.
 
[21]  Takagi T, Ohishi M, Ito N, Kaibe M, Tatara Y, Terai M, et al. “Evaluation of morning blood pressure elevation and autonomic nervous activity in hypertensive patients using wavelet transform of heart rate variability”. Hypertens Res. 2006; 29(12): 977-987.
 
[22]  Fagard RH, Stolarz K, Kuznetsova T, Seidlerova J, Tikhonoff V, Grodzicki T et al. “Sympathetic activity, assessed by Power spectral analysis of heart rate variability, in white-coat, masked and sustained hypertension versus true normotension”. Journal of Hypertension. 2007; 25: 2280-2285.
 
[23]  Pavithran P, Madanmohan MD, RajMithun MBBS, Mathew Jomal MBBS, Nandeesha HMD. “Heart rate variability in middle-aged men with new-onset hypertension.” Ann Noninvasive Electrocardiol 2008; 13(3): 242-248.
 
[24]  Karas M, Larochelle P, LeBlanc RA, Dubé B, Nadeau R, Champlain J. “Attenuation of autonomic nervous system functions in hypertensive patients at rest and during orthostatic stimulation.” The Journal of Clinical Hypertension. 2008; 10(2): 97-104.
 
[25]  Maule S, Rabbia F, Perni V, Tosello F, Bisbocci D, Mulatero P, Veglio F. “Prolonged QT interval and reduced heart rate variability in patients with uncomplicated essential hypertension.” Hypertens Res. 2008; 31(11): 2003-2010.
 
[26]  Havlicekova Z, Tonhajzerova3 I, Jurko Jr A, Jesenak1 M, Durduki P, Nosali S et al.. “Cardiac autonomic control in adolescents with primary hypertension.” Eur J Med Res. 2009; 14(Suppl. IV): 101-103.
 
[27]  Czarnecka D, Posnik-Urbanska A, Kawecka-Jaszcz, Kolasinska-Kloch W, Wojciechowska W, Fedak D. “Indices of autonomic nervous system activity in women with mild hypertension in the perimenopausal period”. KardiologiaPolska 2009; 67: 243-51.
 
[28]  Bajkó Z, Szekeres C, Kovács KR, Csapó K, Monar S, Soltész P, et al. “Anxiety, depression and autonomic nervous system dysfunction in hypertension”. Journal of the Neurological Sciences. 2012; 317(1-2): 112-116.
 
[29]  Çelik A, Koç F, Kad H, Ceyhan K, Erkorkmaz U. “Inflammation is related to unbalanced cardiac autonomic functions in hypertension: an observational study”. AnadoluKardiyolDerg. 2012; 12:233-40.
 
[30]  Guimaraes, Guilherme Veiga; Belli, Juliana Fernanda Canhadas; Bacal, Fernando and Bocchi, Edimar Alcides. “Comportamento dos quimiorreflexos central e periférico na insuficiência cardíaca”. Arq. Bras. Cardiol. 2011;96(2): 161-167.
 
[31]  Gunes, Yilmaz; Guntekin, Unal; Tuncer, Mustafa and Sahin, Musa. “Os efeitos da trimetazidina na variabilidade da frequência cardíaca (VFC) em pacientes com insuficiência cardíaca.” Arq. B.