American Journal of Medical Sciences and Medicine
ISSN (Print): 2327-6681 ISSN (Online): 2327-6657 Website: https://www.sciepub.com/journal/ajmsm Editor-in-chief: Apply for this position
Open Access
Journal Browser
Go
American Journal of Medical Sciences and Medicine. 2021, 9(2), 60-63
DOI: 10.12691/ajmsm-9-2-5
Open AccessArticle

Clinical Characteristics of Children with Corona Virus Disease: Study in a Tertiary Care Hospital, Dhaka, Bangladesh

Mohammed Rizwanul Ahsan1, , Probir Kumar Sarkar2, Nabila Akand3, Kinkar Ghosh4 and Maleeha Sheefa5

1Deptartment of Adolescent Medicine, Dhaka Shishu (Children) Hospital, Dhaka, Bangladesh

2Department of Pulmonology, Dhaka Shishu (Children) Hospital, Dhaka, Bangladesh

3Department. of Paediatric Respiratory Medicine, Dhaka Shishu(Children) Hospital, Dhaka, Bangladesh

4Department of Epidemiology, Dhaka Shishu(Children) Hospital, Dhaka, Bangladesh

5Department of Immunization and Vaccine Development, World Health Organization (WHO), Bangladesh

Pub. Date: May 30, 2021

Cite this paper:
Mohammed Rizwanul Ahsan, Probir Kumar Sarkar, Nabila Akand, Kinkar Ghosh and Maleeha Sheefa. Clinical Characteristics of Children with Corona Virus Disease: Study in a Tertiary Care Hospital, Dhaka, Bangladesh. American Journal of Medical Sciences and Medicine. 2021; 9(2):60-63. doi: 10.12691/ajmsm-9-2-5

Abstract

Background: Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 has spread around the world, and reports of children with COVID-19 are increasing. So for early diagnosis clinical profiles of pediatric COVID-19 patients are important. Methods: A retrospective was done analyzing clinical data from March 15th to 20th july in Dhaka shishu (children) hospital – A tertiary care hospital in Bangladesh. Only admitted patients were included. Results: Among 196 COVID 19 confirmed cases 116 (59.18%) male and 80 (40.82%) female patients were admitted in Medicine Units 160 and in Surgery units 36 patients. Regarding age distribution, 0-30 days aged 26 patients, 1-12 month aged 57 patients, 1-5 years aged patients, 5-10 years aged 42 patients, more than 10 years and less than 18 years aged 14 patients. Most patients came with fever 110 patients, Upper respiratory tract infection (URTS) 74 patients, Lower respiratory tract infection (LRTS) 68 patients, Myalgia 63 patients, Diarrhoea 41 patients, Headache 33 patients, Rash 27 patients, Conjunctivitis 5 patients and 36 patients came with different surgical emergencies. Conclusions: Symptomatic diagnosis of COVID 19 is difficult in children. So all children should be addressed properly. COVID-19 in children is often not serious, with favorable outcomes.

Keywords:
clinical characteristics children corona virus disease

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References:

[1]  N. Zhu, D. Zhang, W. Wang, et al. , A Novel Corona virus from Patients with Pneumonia in China, 2019, Lancet 395 (10223) (2020) 497-506.
 
[2]  Lu R, Zhao X, Li J, et al.: Genomic characterization and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet. 2020, 395: 565-574.
 
[3]  https://www.who.int/dg/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19-11-march-2020.
 
[4]  WHO-China Joint Mission, Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19), (2020) Geneva Accessed March 1, 2020. https://www.who.int/docs/default-source/coronaviruse/who-china-jointmission-on-covid-19 final -report.pdf.
 
[5]  Z.Wu, J. M.Mc Googan, Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72,314 cases from the Chinese center for disease control and prevention, JAMA 323 (13) (2020) 12391242.
 
[6]  D. Wang, X.L. Ju, F. Xie, et al., Clinical analysis of 31 cases of 2019 novel corona virus infection in children from six provinces (autonomous region) of northern China, Zhonghua ErKeZaZhi58 (March2(4)) (2020) E0 11.
 
[7]  D. Sun, H. Li, X. X. Lu, et al., Clinical features of severe pediatric patients with corona virus disease 2019 in Wuhan: a single center’s observational study, World J. Pediatr. (March (19)) (2020).
 
[8]  Y. Dong, X. Mo, Y. Hu, et al., Epidemiology of COVID-19 among children in China, Pediatrics. (March (16)) (2020) e20200702.
 
[9]  W. Xia, J. Shao, Y. Guo, et al., Clinical and CT features in pediatric patients with COVID-19 infection: different points from adults, Pediatr. Pulmonol. (March(5)) (2020).
 
[10]  W. Li, H. Cui, K. Li, et al., Chest computed tomography in children with COVID-19 respiratory infection, Pediatr. Radiol. (March(11)) (2020).
 
[11]  https://dghs.gov.bd/index.php/en/home/5343-covid-19-update.
 
[12]  https://youtu.be/D27IBGeKLx0.
 
[13]  Italian National Health Institute (IstitutoSuperiore di Sanità). Coronavirus epidemic: situation report. March 26, 2020. (In Italian) (https://www.epicentro.iss.it/coronavirus/bollettino/Bollettino­sorveglianza­integrata­COVID­19_26­marzo%202020.pdf).
 
[14]  CDC COVID-19 Response Team. Coronavirus disease 2019 in children—United States, February 12–April 2, 2020. MMWR Morb Mortal Wkly Rep 2020; 69: 422-26.
 
[15]  COVID-19 National Incident Room Surveillance Team. COVID-19, Australia: epidemiology report 11 (reporting week 12 April 2020). Commun Dis Intell 2020; 44.
 
[16]  Gudbjartsson DF, Helgason A, Jonsson H, et al. Spread of SARS-CoV-2 in the Icelandic population. N Engl J Med 2020; published online April 14.
 
[17]  JAMA Pediatr. 2020 May 11. doi: 10.1001/jamapediatrics.2020.1948.
 
[18]  https://doi.org/10.1016/S2352-4642 (20)30177-2.
 
[19]  Cabeça TK, Granato C, Bellei N. Epidemiological and clinical features of human coronavirus infections among different subsets of patients. Influenza Other Respir Viruses. 2013; 7: 1040-1047.
 
[20]  Gaunt ER, Hardie A, Claas EC, et al. Epidemiology and clinical presentations of the four human coronaviruses 229E, HKU1, NL63, and OC43 detected over 3 years using a novel multiplex real-time PCR method. J ClinMicrobiol. 2010; 48: 2940-2947.
 
[21]  Zhang SF, Tuo JL, Huang XB, et al. Epidemiology characteristics of human coronaviruses in patients with respiratory infection symptoms and phylogenetic analysis of HCoV-OC43 during 2010-2015 in Guangzhou. PLoS One. 2018; 13:e0191789.
 
[22]  Friedman N, Alter H, Hindiyeh M, et al. Human coronavirus infections in Israel: epidemiology, clinical symptoms and summer seasonality of HCoVHKU1. Viruses. 2018; 10: 1-9.
 
[23]  Clinical and CT features in pediatric patients with COVID-19 infection: Different points from adults, Pediatric Pulmonology. 2020; 55: 1169-1174.
 
[24]  Children with Covid-19 in Pediatric Emergency Departments in Italy, The New England, Meyer University Children’s Hospital Florence, Italy Journal of Medicine July 9 2020 187.
 
[25]  Xia W, Shao J, Xia W, Shao J, Xia W, Shao J: Clinical and CT features in pediatric patients with COVID‐19 infection: different points from adults. Pediatr Pulmonol. 2020, [Epub ahead of print]:10.1002/ppul.24718.
 
[26]  Vabret A, Mourez T, Gouarin S, et al. An outbreak of coronavirus OC43 respiratory infection in Normandy, France. Clin Infect Dis. 2003; 36: 985-989.
 
[27]  Chiu SS, Chan KH, Chu KW, et al. Human coronavirus NL63 infection and other coronavirus infections in children hospitalized with acute respiratory disease in Hong Kong, China. Clin Infect Dis. 2005; 40:1721-1729.
 
[28]  Davis BM, Foxman B, Monto AS, et al. Human coronaviruses and other respiratory infections in young adults on a university campus: prevalence, symptoms, and shedding. Influenza Other Respir Viruses. 2018; 12: 582-590.
 
[29]  Greenberg SB. Update on human rhinovirus and coronavirus infections. Semin Respir Crit Care Med. 2016; 37: 555-571.
 
[30]  McIntosh K, Kapikian AZ, Turner HC, et al. Sero epidemiologic studies of coronavirus infection in adults and children. Am J Epidemiol. 1970; 91: 585-592.
 
[31]  Esper F, Ou Z, Huang YT. Human coronaviruses are uncommon in patients with gastrointestinal illness. J ClinVirol. 2010; 48: 131-133.
 
[32]  Vabret A, Dina J, Gouarin S, et al. Detection of the new human coronavirus HKU1: a report of 6 cases. Clin Infect Dis. 2006; 42: 634-639.
 
[33]  van der Hoek L, Pyrc K, Jebbink MF, et al. Identification of a new human coronavirus. Nat Med. 2004; 10: 368-373.