American Journal of Medical Case Reports
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American Journal of Medical Case Reports. 2017, 5(5), 116-118
DOI: 10.12691/ajmcr-5-5-3
Open AccessCase Report

Rifabutin low dose-induced intermediate uveitis in a patient with Acquired Immunodeficiency Syndrome

Agustina C. Palacio1, Mercedes Cabrini2, Graciela Ben2 and Emilio M. Dodds1,

1Department of Ophthalmology, Consultores Oftalmológicos, Buenos Aires, Argentina

2Department of infectology, Hospital General de Agudos Juan A. Fernandez, Buenos Aires, Argentina

Pub. Date: June 03, 2017

Cite this paper:
Agustina C. Palacio, Mercedes Cabrini, Graciela Ben and Emilio M. Dodds. Rifabutin low dose-induced intermediate uveitis in a patient with Acquired Immunodeficiency Syndrome. American Journal of Medical Case Reports. 2017; 5(5):116-118. doi: 10.12691/ajmcr-5-5-3


Intermediate uveitis is a relatively rare manifestation of Rifabutin induced uveitis. Rifabutin toxicity is unusual at doses of 300 mg daily or less. The purpose of this study is to report the case of an HIV+ patient with unilateral rifabutin induced intermediate uveitis after 4 months of treatment with low dose rifabutin (150 mg daily) in combination with ritonavir and fluconazole. The uveitis resolved after drug discontinuance and the use topical corticosteroids.

Rifabutin drug induced uveitis intermediate uveitis vitritis drug interaction

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