American Journal of Medical Case Reports. 2017, 5(2), 48-49
DOI: 10.12691/ajmcr-5-2-7
Open AccessCase Report
Zainab Jalal1, Asad Ullah2, , Ladan Mohammadi1 and Jeanne Spencer1
1Department of Family Medicine, Conemaugh Memorial Medical Center, Johnstown, PA
2Department of Internal Medicine, Conemaugh Memorial Medical Center, Johnstown, PA
Pub. Date: March 07, 2017
Cite this paper:
Zainab Jalal, Asad Ullah, Ladan Mohammadi and Jeanne Spencer. Thyrotoxic Hypokalemic Periodic Paralysis. American Journal of Medical Case Reports. 2017; 5(2):48-49. doi: 10.12691/ajmcr-5-2-7
Abstract
Thyrotoxic hypokalemic periodic paralysis (THPP) is a sporadic form of hypokalemic periodic paralysis (HPP), a rare disease which is manifested as painless muscle weakness in the presence of hyperthyroidism and hypokalemia. Our patient was recently diagnosed with hyperthyroidism due to Graves’ disease and was started on antithyroid therapy. He presented few months later with upper and lower extremity weakness along with finding of hypokalemia in the background of hyperthyroidism. He was given potassium replacement therapy with resolution of symptoms.Keywords:
thyrotoxic hypokalemic periodic paralysis hyperthyroidism hypokalemia potassium replacement
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References:
[1] | Jurkat-Rott, K., et al., A calcium channel mutation causing hypokalemic periodic paralysis. Hum Mol Genet, 1994. 3(8): p. 1415-9. |
|
[2] | Bulman, D.E., et al., A novel sodium channel mutation in a family with hypokalemic periodic paralysis. Neurology, 1999. 53(9): p. 1932-6. |
|
[3] | Jennette, J. and D. Tauferner, Paralysis as a Presenting Symptom of Hyperthyroidism in an Active Duty Soldier. US Army Med Dep J, 2015: p. 48-50. |
|
[4] | Lin, S.H., Y.F. Lin, and M.L. Halperin, Hypokalaemia and paralysis. QJM, 2001. 94(3): p. 133-9. |
|
[5] | Catalano, C., et al., Hypokalaemia with paralysis: don't forget the thyroid. BMJ Case Rep, 2011. 2011. |
|
[6] | Pompeo, A., et al., Thyrotoxic hypokalemic periodic paralysis: An overlooked pathology in western countries. Eur J Intern Med, 2007. 18(5): p. 380-90. |
|