American Journal of Medical Case Reports. 2016, 4(5), 150-152
DOI: 10.12691/ajmcr-4-5-1
Open AccessCase Report
Modupeola O. Samalia1, Tara Chang2, M. Ruhul Quddus3, , C. James Sung3, Katrine Hansen3 and W. Dwayne Lawrence3
1Department of Pathology & Morbid Anatomy, Ahmadu Bello University & Ahmadu Bello University Teaching Hospital, Zaria, Nigeria
2Middle Tennessee Medical Center, Murfreesboro, TN
3Department of Pathology, Women & Infants Hospital, Alpert Medical School of Brown University, Providence, RI, USA
Pub. Date: May 04, 2016
Cite this paper:
Modupeola O. Samalia, Tara Chang, M. Ruhul Quddus, C. James Sung, Katrine Hansen and W. Dwayne Lawrence. Mullerian Adenosarcoma Occurring in a Young Female and Originally Diagnosed as an Endometrial Stromal Nodule. American Journal of Medical Case Reports. 2016; 4(5):150-152. doi: 10.12691/ajmcr-4-5-1
Abstract
Mullerian Adenosarcoma (MA) is most commonly encountered in postmenopausal females in the sixth decade of life. We present the case of a 21-year old female with a high BMI and a clinical presentation suggestive of polycystic ovarian disease; she presented with abnormal vaginal bleeding. A laparoscopy/hysteroscopy by her primary physician demonstrated an intracavitary and submucosal appearing mass which was clinically considered to be a polypoid submucosal leiomyoma. The patient underwent endometrial curettage. The specimen was comprised of multiple fragments of soft tan-red haemorrhagic tissues aggregating to 6.5 x 4.0 x 0.6 cm. An original diagnosis of endometrial stromal nodule was made on this material; however, on consultative review the diagnosis was changed to a mullerian adenosarcoma. No stromal overgrowth or heterologous differentiation was identified. Immunohistochemical studies demonstrated stromal cells were positive for oestrogen receptor (ER) and CD10. We emphasize the young age of this patient with a mullerian adenosarcoma as well as the pitfall of making a specific diagnosis of endometrial stromal neoplasms based on an endometrial curettage.Keywords:
Mullerian Adenosarcoma endometrial stromal nodule submucosal mass endometrial curettage young patient diagnostic pitfall
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