Pulmonary Adenofibroma; A Rare Finding

Heidarali Esmaeili¹, Mahzad Azimpouran^1, , Behrouz Shokohi¹, Elmira Mostafidi¹ and Mahsa Karbasi²

¹Department of General Pathology, Tabriz University of Medical Science, Tabriz, Iran

²Department of Radiology, Tabriz University of Medical Science, Tabriz, Iran

Cite this paper:
Heidarali Esmaeili, Mahzad Azimpouran, Behrouz Shokohi, Elmira Mostafidi and Mahsa Karbasi. Pulmonary Adenofibroma; A Rare Finding. American Journal of Medical Case Reports. 2016; 4(3):101-107. doi: 10.12691/ajmcr-4-3-8

Abstract

Pulmonary adenofibroma is a rare lung benign tumor resembling adenofibroma of the breast and genital tract. Few cases have been reported with this entity. We report a case of pulmonary adenofibroma in a 65-year-old female, which was found incidentally through the work up for her gastrointestinal problems. Chest radiograph and computed tomography scan disclosed a well circumscribed pulmonary mass at left lower lung lobe. Surgical excision was done and the specimen studied macroscopically and microscopically. Histological findings revealed a biphasic lesion showing a leaflike fibroepithelial pattern with stromal and epithelial components. Immunohistochemical studies showed positivity for pan cytokeratin (CK), CD34, vimentin, smooth muscle actin (SMA), but negative for S100 and calretinin. The patient had neither symptoms nor recurrence through one and half year follows up.

Keywords:
Pulmonary Lung Adenofibroma benign tumor immunohistochemistry (IHC)

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