Rhinosinusitis Caused by Unusual Fungus Fonsecaea pedrosoi - A Rare Case Report from South India

Chadiesh Nagarajan¹, Premamalini Thayanidhi², Rajyoganandh Subramanian Vijayaraman², Anupma Jyoti Kindo^2, and John Samuel³

¹Department of Microbiology, Apollo Specialty Hospitals, Trichy, India

²Department of Microbiology, Sri Ramachandra Medical College and Research Institute, Porur, Chennai, Tamil Nadu, India

³Department of Oto-Rhino-Laryngology, Sri Ramachandra Medical College and Research Institute, Porur, Chennai, Tamil Nadu, India

Cite this paper:
Chadiesh Nagarajan, Premamalini Thayanidhi, Rajyoganandh Subramanian Vijayaraman, Anupma Jyoti Kindo and John Samuel. Rhinosinusitis Caused by Unusual Fungus Fonsecaea pedrosoi - A Rare Case Report from South India. American Journal of Medical Case Reports. 2015; 3(9):297-300. doi: 10.12691/ajmcr-3-9-9

Abstract

Phaeohyphomycosis causing rhinosinusitis is not very frequent. We here report a case of rhinosinusitis caused by Fonsecaea pedrosoi in a 53 year old diabetic male, with deviated nasal septum. With surgical correction and antifungal treatment with itraconazole, the patient’s condition improved and he was discharged. Fonsecaea exists in the environment as a saprophyte and its infection is usually not lethal. However in immunocompromised individuals, when there is systemic invasion the mortality rate is high. With limited treatment options available for this fungus, early and prompt identification plays a major role not only in treatment, but also prevents further invasion.

Keywords:
phaeohyphomycosis Fonsecaea pedrosoi fungal rhinosinusitis

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References:

[1]	Chakrabarti A, Sharma SC. Paranasal sinus mycoses. Indian J Chest Dis Allied Sci 2000;42:293-304.
[2]	Chakrabarti A, Denning DW, Ferguson BJ, Ponikau J, Buzina W, Kita H et al. Fungal rhinosinusitis: a categorization and definitional schema addressing current controversies. Laryngoscope 2009 Sep; 119(9):1809-18.
[3]	deShazo RD, Chapin K, Swain RE. Fungal sinusitis. N Engl J Med 1997; 337:254-259.
[4]	Brandt ME, Warnock DW. Epidemiology, clinical manifestations, and therapy of infections caused by dematiaceous fungi. J Chemother 2003;15:36-47.
[5]	de Hoog GS, Attili-Angelis D, Vicente VA, et al. Molecular ecology and pathogenic potential of Fonsecaea species. Med Mycol 2004; 42(5): 405-16.
[6]	Najafzadeh MJ, Gueidan C, Badali H, et al. Genetic diversity and species delimitation in the opportunistic genus Fonsecaea. Med Mycol 2009; 47(1): 17-25.
[7]	de Hoog GS, Guarro J, Gene J, Figueras MJ. Atlas of Clinical Fungi (2nd ed.). Netherlands: Centraal bureau voor Schimmelcultures; 2000:679-80.
[8]	Rees JR, Pinner RW, Hajjeh RA Brandt ME, Reingold AL. The epidemiological features of invasive mycotic infections in the San Francisco Bay area, 1992-1993: results of population-based laboratory active surveillance. Clin Infect Dis 1998; 27:138-47.
[9]	Mehta, S. A., S. Kaul, M. S. Mehta, R. S. Kelkar, and A. R. Mehta.Phaehyphomycosis of the paranasal sinuses masquerading as a neoplasm: A case report. Head Neck Surg 1993; 15: 59-61.
[10]	Gungor A, Adusumilli V. Fungal sinusitis: progression of diseases in immunosuppression- A case report. Ear Nose Throat J 1998; 77: 207-15.
[11]	McGinnis. M.R. Laboratory handbook of Medical Mycology. London:Academic Press; 1980.