Extra-Ocular Sebaceous Carcinoma of the Skin: A Report of Five Cases and a Review of the Literature

Mariem MOHAMED^1, , Lobna BOUSSOFARA², Abdlefaddeh SLAMA³, Mohamed DENGUEZLI², Colandane BELAJOUZA², Bedreddine SRIHA⁴, Najet GHARIANI² and Rafiaa NOUIRA²

¹Dermatology Department, Fattouma Bourguiba University Hospital, Monastir, Tunisia

²Dermatology Departments, Farhat Hached University Hospital, Sahloul University Hospital, Sousse, Tunisia

³Oral and Maxillo-Facial Surgery Department, Sahloul University Hospital, Sousse, Tunisia

⁴Pathology Departments, Farhat Hached University Hospital, Sahloul University Hospital, Sousse, Tunisia

Cite this paper:
Mariem MOHAMED, Lobna BOUSSOFARA, Abdlefaddeh SLAMA, Mohamed DENGUEZLI, Colandane BELAJOUZA, Bedreddine SRIHA, Najet GHARIANI and Rafiaa NOUIRA. Extra-Ocular Sebaceous Carcinoma of the Skin: A Report of Five Cases and a Review of the Literature. American Journal of Medical Case Reports. 2015; 3(9):291-296. doi: 10.12691/ajmcr-3-9-8

Abstract

Background: Extra ocular sebaceous carcinoma is a rare aggressive adnexal tumour. The diagnosis of this tumour is difficult due to the variety of its clinical and histopathological features. The prognosis is actually considered as aggressive as the ocular counterpart. Methods and results: We propose to discuss the clinical features, histopathological findings and aggressive potential of extra ocular sebaceous carcinoma. Therefore, five extra ocular sebaceous carcinoma cases, diagnosed at the Dermatology and Pathology departments of Farhat Hached Hospital, from January 1998 to December 2007, were reviewed. The diagnosis was based on a histopathological examination. Three of them developed locoregional and/or distant metastases. One patient died from metastatic disease. Surgery was the mainstay of treatment without any cutaneous recurrence after a mean follow-up of two years. Conclusions: Extra ocular sebaceous carcinoma has an unpredictable prognosis. It can be highly aggressive and cause death. Surgery remains the mainstay of treatment.

Keywords:
sebaceous adenocarcinoma extra ocular sebaceous carcinoma skin cancer prognosis surgery

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