Primary Splenic Diffuse Large B Cell Lymphoma after Splenectomy: A Rare Case with Literatur Review

Semra Ayturk¹, Mehmet Celik^1, , Onur Mert², Nuray Can³, Atakan Sezer⁴, Sibel Guldiken¹ and Ahmet Muzaffer Demir⁵

¹Department of Internal Medicine, Division of Endocrinology and Metabolism, Trakya Medical School, University of Trakya, Edirne, Turkey

²Department of Internal Medicine, Trakya Medical School, University of Trakya, Edirne, Turkey

³Department of Pathology, Trakya Medical School, University of Trakya, Edirne, Turkey

⁴Department of General Surgery, Trakya Medical School, University of Trakya, Edirne, Turkey

⁵Department of Internal Medicine, Division of Hematology, Trakya Medical School, University of Trakya, Edirne, Turkey

Cite this paper:
Semra Ayturk, Mehmet Celik, Onur Mert, Nuray Can, Atakan Sezer, Sibel Guldiken and Ahmet Muzaffer Demir. Primary Splenic Diffuse Large B Cell Lymphoma after Splenectomy: A Rare Case with Literatur Review. American Journal of Medical Case Reports. 2015; 3(8):265-268. doi: 10.12691/ajmcr-3-8-11

Abstract

Primary splenic diffuse large B cell lymphoma is rarely clinical entity and comprises 1% of all malignant lymphomas. The spleen is also involved in immune defense against blood-borne antigens. Though the haematological malignancies, spleen is usually affected as a part of multisystemic involvement rather than isolated involvement. More than half of patients affected by Hodgkin's disease and about a third of those with non-Hodgkin lymphoma have splenic involvement. The involved spleen may be complicated with rupture due to massive splenomegaly, which may need urgent intervention. In this report, we present a 47-year-old female patient with massive splenomegaly, who was diagnosed with primary splenic diffuse large B cell lymphoma after splenectomy.

Keywords:
diffuse large B-cell lymphoma splenomegaly splenic neoplasms

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