Malignant Peripheral Nerve Sheath Tumor of Buccal Mucosa: An Oncological Surprise

Ram Abhinav Kannan^1, , Kirthi Koushik¹, Usha Muniyappa², Ritika Harjani¹ and Arvind Murthy¹

¹Department of Radiation Oncology, M S Ramaiah Medical College, Bangalore, India

²Department of Pathology, M S Ramaiah Medical College, Bangalore, India

Cite this paper:
Ram Abhinav Kannan, Kirthi Koushik, Usha Muniyappa, Ritika Harjani and Arvind Murthy. Malignant Peripheral Nerve Sheath Tumor of Buccal Mucosa: An Oncological Surprise. American Journal of Medical Case Reports. 2014; 2(10):222-224. doi: 10.12691/ajmcr-2-10-6

Abstract

Malignant peripheral nerve sheath tumors are aggressive sarcomas with poor prognosis. It is usually encountered in lower extremities. Only a few cases have been reported in head and neck region with buccal mucosa being an unusual site.

Keywords:
malignant peripheral nerve sheath tumor radiation surgery

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References:

[1]	Barnes L, Dekker M. Surgical pathology of the head and neck. Tumours of the Head and Neck. 2nd ed. Madison Avenue Inc; New York; 2001. p. 836-41.
[2]	Eversole LR, Schwart DW, Sabes WR. Central and peripheral fibrogenic and neurogenic sarcoma of the oral region. Oral Surg 1973; 36(1): 49-62.
[3]	Rosen FS, Pou AM. Obstructive supraglottic schwannoma: A case report and review of the literature. Laryngoscope 2002; 112: 997-1002.
[4]	Colreavy MP, Lacy PD, Hughes J. Head and neck schwannomas – A 10 year review. J Laryngol Otol 2000; 114: 119-124.
[5]	R. E. Ferner and D. H. Gutmann. International consensus statement on malignant peripheral nerve sheath tumors in neurofibromatosis. Cancer Research 2002; 62( 5): 1573-1577.
[6]	Lee JH, Lee HK, Choi CG, Suh DC, Lee KS, Khang SK. Malignant peripheral nerve sheath tumour in the parapharyngeal space: Am J Neuroradiol 2001; 22: 748-50.
[7]	Kumar V, Abbas AK, Fasto N, Robins, Cotrans. Pathologic basis of diseases. 7th ed. Saunders: Philadelphia; 2004. p. 1413-21.
[8]	Ahsan F, Lee MK, Ah-See KW, Chapman AD. Malignant peripheral nerve sheath tumour of the paranasal sinuses. Ear Nose Throat J 2004; 83: 699-701.
[9]	Regezi JA, Sciubba JJ, Jordan RC. Clinical pathologic correlations Connective tissue lesions oral pathology. 4th ed Philadelphia; 2003. p. 17.
[10]	Cawson RA, Binne WH, Barrett AW, Wright JM. Oral diseases, tumours and tumour like lesions of soft tissues. 3rd ed. Saunders: Philadelphia; 2001. p. 10.21-2.
[11]	Sheikh OA, Reaves A, Kralick FA, Brooks A, Musial RE,e and James Gasperino J. Malignant nerve sheath tumor of the spinal accessory nerve: a unique presentation of a rare tumor.Journal of Clinical Neurology 2012; 8: 75-78.
[12]	Munhoz EA, Cardoso CL, Tolentino ES, Centurion BS, Gonçales ES, Sant’Ana E et al. Von Recklinghausen’s disease- diagnosis from oral lesion. Neurofibromatosis 1. International Journal of Odontostomatology 2010;.4:179-183.
[13]	Gupta J, Gupta KK, Jaiswal R, Vashist H. MPNST- A Diagnostic Dilemma. Indian Journal of Dental Sciences 2013; 5: 126-129.
[14]	Hruban RH, Shiu MH, Senie RT, Woodruff JM. Malignant peripheral nerve sheath tumors of the buttock and lower extremity: A study of 43 cases. Cancer 1990; 66(6): 1253-65.
[15]	Ducatman BS, Scheithauer BW, Piepgras DG, Reiman HM, Ilstrup DM. Malignant peripheral nerve sheath tumors: A clinicopathologic study of 120 cases. Cancer 1986; 57(10): 2006-21.
[16]	Stucky CC, Johnson KN, Gray RJ, Pockaj BA, Ocal IT, Rose PS, et al. Malignant peripheral nerve sheath tumors (MPNST): the Mayo Clinic experience. Annals of surgical oncology. Mar 2012; 19(3): 878-885.
[17]	Zou C, Smith KD, Liu J, Lahat G, Myers S, Wang WL. Clinical, pathological, and molecular variables predictive of malignant peripheral nerve sheath tumor outcome. Ann Surg. 2009 Jun; 249(6): 1014-22.