Challenging Discontinuation of Sedation in the Intensive Care Unit May Potentially be Attributed to Thiamine Deficiency. Case Report

Dr. S. AlKaabi¹, Dr. R. Ebead¹, Dr. M. Khames^1, , Dr. M. Amin¹, Dr. A. Gupta¹, Dr. E. Marzouk¹ and Dr. S. Ahmed¹

¹ICU department Zayed Military Hospital Abu Dhabi, UAE

Cite this paper:
Dr. S. AlKaabi, Dr. R. Ebead, Dr. M. Khames, Dr. M. Amin, Dr. A. Gupta, Dr. E. Marzouk and Dr. S. Ahmed. Challenging Discontinuation of Sedation in the Intensive Care Unit May Potentially be Attributed to Thiamine Deficiency. Case Report. American Journal of Medical Case Reports. 2024; 12(3):38-41. doi: 10.12691/ajmcr-12-3-3

Abstract

This is a case of 54-years-old critically ill H1N1 ARDS patient with prolonged ventilation and sedation and difficult weaning from sedation and mechanical ventilation. The case gives spotlight on not uncommon cause of delirium and failure of weaning in critically ill patients which is Vitamin B1 deficiency and how it is underestimated and should be put in mind while management those patients. Delirium and the failure to wean patients off sedation and mechanical ventilation in intensive care units (ICUs) are significant challenges that healthcare providers frequently face. This issue became evident in a unique case involving a critically ill H1N1 ARDS patient aged 54, which highlighted the often-ignored cause of these complications - Vitamin B1 deficiency. This critical review aims to delve deeper into the role of Vitamin B1 deficiency in exacerbating the conditions of critically ill patients and argue why it should be a key consideration in patient management.

Keywords:
Acute delirium acute confusion state thiamine deficiency encephalopathy sedation weaning ventilator weaning ICU critically ill

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