Novel Pseudoangiomatous Stromal Hyperplasia Mass in a Breast Hamartoma: A Case Report

Beau Doerr^1, , Shemar Crawford², Brian Nykanen² and Cole Burr³

¹Touro College of Osteopathic Medicine - Middletown Campus, 60 Prospect Ave, Middletown, NY, 10940

²Florida State College of Medicine, 1115 W Call Street, Tallahassee, FL, 32304

³Department of Radiology, Tripler Army Medical Center, 1 Jarrett White Road, Honolulu, HI, 96859

Cite this paper:
Beau Doerr, Shemar Crawford, Brian Nykanen and Cole Burr. Novel Pseudoangiomatous Stromal Hyperplasia Mass in a Breast Hamartoma: A Case Report. American Journal of Medical Case Reports. 2022; 10(12):307-310. doi: 10.12691/ajmcr-10-12-3

Abstract

Breast fibroadenolipomas, otherwise known as hamartomas, are a relatively rare finding in regard to the occurrence of breast masses. Breast hamartomas make up approximately 4.8% of benign breast tumors in women. Breast hamartomas are uncommon, and our case presents with a 4.7 cm hamartoma with a focal, irregular mass inside of it which was histologically confirmed as pseudoangiomatous stromal hyperplasia (PASH). PASH is a benign mesenchymal lesion of the breast that is characterized by dense collagenous stroma forming “pseudoangiomatous” capillary-like spaces lined by spindle cells. [1] A rare condition overall, PASH is predominately discovered in premenopausal women, with fewer than 1,500 cases of PASH documented in literature [1]. Therefore, our case presentation describes a combination of two relatively rare phenomena within one palpable breast mass. Due to the absence of symptoms, the patient was scheduled for interval follow up to monitor the breast hamartoma for interval change in size, and definitive treatment by elective surgical excision was offered if accompanying symptoms developed.

Keywords:
breast hamartoma breast mass pseudoangiomatous stromal hyperplasia ultrasound mammography

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