Sevelamer Induced Colitis Causing Deep Cratered Ulcer in an End-Stage Renal Disease Patient

Shawn Philip^1, , Muhammad Farhan Ashraf¹, Mary Strader², Hala Abdelwahab³ and Asra Batool²

¹Albany Medical Center, Department of Internal Medicine, Albany, NY. USA

²Albany Medical Center, Department of Gastroenterology, Albany, NY. USA

³Albany Medical Center, Department of Pathology, Albany, NY. USA

Cite this paper:
Shawn Philip, Muhammad Farhan Ashraf, Mary Strader, Hala Abdelwahab and Asra Batool. Sevelamer Induced Colitis Causing Deep Cratered Ulcer in an End-Stage Renal Disease Patient. American Journal of Medical Case Reports. 2022; 10(6):173-175. doi: 10.12691/ajmcr-10-6-3

Abstract

Sevelamer is phosphate lowering oral agent used in chronic kidney disease (CKD) to decrease oral phosphate absorption. Sevelamer has been shown to cause crystalline induced colitis. This can manifest as abdominal pain or gastrointestinal bleeding. We present a case with chronic kidney disease and Moyamoya syndrome that presented with abdominal pain and anemia. Colonoscopy revealed a single circumferential cratered ulcer in the transverse colon. Pathology showed crystalline induced colitis. Sevelamer was discontinued and the patient`s symptoms improved.

Keywords:
Sevelamer colitis ulcer

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