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American Journal of Medical and Biological Research. 2015, 3(1), 33-37
DOI: 10.12691/ajmbr-3-1-2
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The Changes of the Cellular Indicators of Leucopoiesis in Irradiated Animals under Hypomotile Conditions

Vitali Kalantaryan1, , Tsovinar Adamyan2, Emma Gevorkyan2, Nona Adamyan2 and Tigran Hayrapetyan2

1Department of Microvawe Radiophysics and Telecommunication, Yerevan State University, Alex Manoogian str.1, Yerevan 0025, Armenia

2Department of Human and Animals Phisiology, Yerevan State University, Alex Manoogian str.1, Yerevan 0025, Armenia

Pub. Date: February 11, 2015

Cite this paper:
Vitali Kalantaryan, Tsovinar Adamyan, Emma Gevorkyan, Nona Adamyan and Tigran Hayrapetyan. The Changes of the Cellular Indicators of Leucopoiesis in Irradiated Animals under Hypomotile Conditions. American Journal of Medical and Biological Research. 2015; 3(1):33-37. doi: 10.12691/ajmbr-3-1-2


It is studied the nature of the changes of the morpho-functional indicators of leukopoiesis in hypokinesia dynamics on the background of multiple impact of the millimeter range electromagnetic waves. It is shown that the preliminary radiation increases the potential capacity of the regulatory systems of leukopoiesis, activates the proliferative and maturation processes of the stem cells, and boosts the adaptive compensatory mechanisms thus resulting in preventing of the negative impact of hypokinesis.The obtained data allow us to assume that the low-power microwaves with the frequency of 42.2 GHz are means of non-medicational treatment under stress rectifying the changes of the morpho-functional indicators.The changes in the sympathoadrenal system, the increase of the immunoreactivity and non-specific resistance, the activization of endogenetic immunomodulators have important role in the mechanism of the physiological impact of non-ionizing millimeter electromagnetic waves.

hypokinesia millimeter electromagnetic waves leukopoiesis non-ionizing radiation

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[1]  Molokanova V, Shigabutdinova E and Makarova L 2004 Correction immunobiochemical status of animals under lengthy period of adaptation to hypokinesia Modern science technologies 4 13-16 Troitsk.
[2]  Latyushin Ya 2010 Regularities of molecular and cellular adaptation processes in the blood system in acute and chronic hypokinetic stress Abstract of dissertation Dr.Sci.Biol Chelyabinsk 33pp.
[3]  Grigoryan A 1993 Effect of hypokinesia on some aspects of the metabolism and the natural resistance of animals Abstract of Ph.D. thesis of veterinary sciences 27 pp.
[4]  Chanieva M 2012 Erythrocyte and thrombocytic indicators of peripheral blood in conditions simulating microgravity and hyperkinesias Abstract of dissertation MD Moscow 23p.
[5]  Devyatkov N and Betskiy O 1985 Features of low -intensity millimeter radiation interaction with biological objects Report digests. Low-intensity millimeter radiation application in biology and medicine IRE AN USSR Moscow.
[6]  Presman A 1998 Electromagnetic fields and wildlife Nauka 228pp Moscow.
[7]  Devyatkov N, Betsky O and Golant M 1991 Millimeter waves and their role in the processes of life Radio and Svyaz, Moscow.
[8]  Chuyan E and Makhonina M 2005 Synthetic activity of lymphocytes: the effect of radiation of millimeter range Millimeter waves in biology and medicine 1 32-6.
[9]  Rojavin M and Ziskin M 1998 Medical application of millimeter waves QJ Med 91 57-6.
[10]  Minasyan S, Grigoryan G, Saakyan S, Akhumyan A and Kalantaryan V 2007 Effects of the Action of Microwave-Frequency Electromagnetic Radiation on the Spike Activity of Neurons in the Supraoptic Nucleus of the Hypothalamus in Rats.Neuroscience and Behavioral Physiology (USA) 37 N 2 175-80.
[11]  Tadevosyan H, Kalantaryan V and Trchounian A 2008 Extremely High Frequency Electromagnetic Radiation Enforces Bacterial Effects of Inhibitors and Antiobiotics. Cell Biochemestry & Biophysics 51(2-3) 97-103 July.
[12]  Kalantaryan V, Vardevanyan P, Babayan Y, Gevorkyan E, Hakobyan S and Antonyan A 2010 Influence of low intensity coherent electromagnetic millimeter radiation (EMR) on aqua solution of DNA. Progress In Electromagnetics Research Letters 13 1-9.
[13]  Torgomyan H, Kalantaryan V and Trchounian A 2011 Low Intensity Electromagnetic Irradiation with 70.6 and 73 GHz Frequencies Affects Escherichia coli Growth and Changes Water Properties. Cell Biochemestry & Biophysics 60(3) 275-81.
[14]  Kalantaryan V, Martirosyan R, Nersesyan L, Aharonyan A, Danielyan I, Stepanyan H, Gharibyan J and Khudaverdyan N 2011 Effect on tumoral cells of low intensity electromagnetic waves Progress In Electromagnetics Research Letters 20 98-105.
[15]  Torgomyan H, Ohanyan V, Blbulyan S, Kalantaryan V and Trchounian A 2012 Electromagnetic irradiation of Enterococcus hirae at low-intensity 51.8- and 53.0-GHz frequencies: changes in bacterial cell membrane properties and enhanced antibiotics effects. FEMS Microbiology Letters Apr., 329(2), 131-37.
[16]  Kalantaryan V, Martirosyan R, Babayan Y, Nersesyan L and Stepanyan H 2014 Preliminary Results of Influence of Nonionizing Electromagnetic Radiation on Tumor and Healthy DNA and Role of Water American Journal of Medical and Biological Research 2(1) 18-25.
[17]  Temuryants N and Chuyan E 1992 Effect of microwaves of nonthermal intensity on the development of hypokinetic stress in rats with different individual characteristics Millimeter waves in biology and medicine 1 22-32.
[18]  Temuryants N, Chuyan E and Tumanyants E 1993 Dependence of the anti-stress action of electromagnetic radiation of millimeter range from impact localization in rats with different typological features Millimeter waves in biology and medicine 2 51-8.
[19]  Kirichuk V, Antipova O, Andronov E, IvanovA, Krenitski A and Mayborodin A 2009 Efficiency of the different modes THz-radiation waves on restoration of rheology properties of the blood under stress-reaction with white rats Biomedical Radioelectronics 6 55-62.
[20]  Chuyan E 2008 Physiological mechanisms of biological action of low-intensity electromagnetic radiation of extremely high frequency Millimeter waves in biology and medicine 2(50) 10-44.
[21]  Pshennikova M 2001 Stress phenomenon. Emotional stress and its role in pathology Patologicheskaia fiziologiia 2 26-30.
[22]  Galeeva A and Zhukov D 1996 Behavioural and endocrine responses to the emotional stress in rats strains selected for divergent acquisition of active avoidance Zhurnal visshei nervnoi deyatelnosti imeni I.P. Pavlova 46(5) 929-36.
[23]  Venglinskaya E, Rukavtsov B, et al. 1978 A comparative study of functional activity and cytochemical characteristics of human and rabbit microphages”, Journal of hygiene, epidemiology, microbiology, and immunology 22(1) 83-9.
[24]  Lushnikov K, Gapeyev A and Chemeris N 2002 Effects of extremely high-frequency electromagnetic radiation on the immune system and systemic regulation of homeostasis Radiatsionnaia biologiia, radioecologiia /Rossiiskaia akademiia nauk/ 42(5) 533-45.
[25]  Goldberg E, Dygai A and Zhdanov V 2006 Role of stem cells in restoring hematopoiesis with cytostatic and radiation myelosuppressions Bulletin of the Siberian medicine 2 35-42.
[26]  Chrousos, G.P. and P.W.Gold, “The concepts of stress system disorders: overview of beheuvioral and physical homeostasis”, J. A.M.A. Vol.267, 1244-1252, 1992.
[27]  Panin, L. E. “Biochemical mechanisms of stress.” Nauka, Novosibirsk, 232pp, 1983.
[28]  Chuyan, E.N. and N.A.Temuryants, “Neuro-immune-endocrine mechanisms of adaptation to low-intensity electromagnetic radiation of extremely high frequency”, Millimeter waves in biology and medicine, Vol.3(39), 17-31, 2005.
[29]  Zhukova, G.V., L.H.Garkavi, O.F.Eustratova, E.U.Zlatnik, T.A.Barteneva, E.A.Kipelova et al. “State of some immune structures under antitumoral effects of combined action of Skenar-therapy and modulated EHF EMR in experiments”. Biomedical technology and radioelectronics 8 10-17 2005.
[30]  Malnsky A and Malnsky D 1983 Essays on neutrophils and macrophages Novosibirsk. Science, 256 pp.