Detection of Nocardia from Chronic Skin and Lung Infections in Bangladeshi Patients

Afzalunnessa Binte Lutfor^1, , Ritu Saha¹, Arpita Deb¹, Asif Mujtaba Mahmud², Abu Ahmed Ashraf Ali¹, Tasmin Haque¹, Sadia Rahman¹, Nadia Sharmin Shorno³ and Amina Arafat¹

¹Department of Microbiology, Ad-din Women’s Medical College Hospital, Dhaka, Bangladesh

²Department of Respiratory Medicine, Asgar Ali Hospital, Dhaka, Bangladesh

³Department of Critical care & Emergency Medicine, Dhaka Medical College Hospital, Dhaka, Bangladesh

Cite this paper:
Afzalunnessa Binte Lutfor, Ritu Saha, Arpita Deb, Asif Mujtaba Mahmud, Abu Ahmed Ashraf Ali, Tasmin Haque, Sadia Rahman, Nadia Sharmin Shorno and Amina Arafat. Detection of Nocardia from Chronic Skin and Lung Infections in Bangladeshi Patients. American Journal of Infectious Diseases and Microbiology. 2017; 5(2):80-86. doi: 10.12691/ajidm-5-2-2

Abstract

Nocardiosis is an acute or chronic infectious disease that may occur in cutaneous, pulmonary and disseminated form in both immunocompromised and immunocompetent host. It may become potentially severe due to delayed diagnosis and incomplete or ineffective treatment. So the aim of the study was to isolate Nocardia spp. from suspected samples, mainly from chronic unhealed wounds and to identify appropriate antimicrobials by susceptibility testing in Bangladeshi patients. Methods: From January 2015-2017, 62 samples were collected which were studied for Nocardial identification and susceptibility testing. Results: Out of total 62 cases, 18 (29.03%) cases were Nocardia positive cases. Besides 6 Acinetobacter spp. and 2 Actinomyces spp. with other varied pathogens were isolated. Among 18 identified nocardiosis patients, majority (10) were post surgery cases, 6 suspected skin and glandular tuberculosis (TB) cases, one had breast sinus, and one was suspected pulmonary TB case. In terms of susceptibility of nocardial isolates, 100% were susceptible to linezolid, 88.9% to amikacin and 78% to trimethoprim-sulphamethoxazole.

Keywords:
chronic skin infection discharging sinus Nocardia non healing wound primary cutaneous nocardiosis

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