American Journal of Epidemiology and Infectious Disease
ISSN (Print): 2333-116X ISSN (Online): 2333-1275 Website: https://www.sciepub.com/journal/ajeid Editor-in-chief: John Opuda-Asibo
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American Journal of Epidemiology and Infectious Disease. 2014, 2(4), 97-100
DOI: 10.12691/ajeid-2-4-3
Open AccessArticle

Retrospective Cross-sectional Study of Dengue Cases in IPD with Reference to Treatment- Monitoring & Outcome in KEM Hospital, Mumbai

Anil Pardeshi1, , Ratnendra Shinde2, Abhijeet Jagtap1, Ravindra Kembhavi2, Mayur Giri2 and Snehal Kavathekar1

1P.G. scholars of School of Pharmaceutical-Medicine

2Department of Community Medicine, Seth G. S. Medical College & KEM Hospital, Parel, Mumbai

Pub. Date: September 26, 2014

Cite this paper:
Anil Pardeshi, Ratnendra Shinde, Abhijeet Jagtap, Ravindra Kembhavi, Mayur Giri and Snehal Kavathekar. Retrospective Cross-sectional Study of Dengue Cases in IPD with Reference to Treatment- Monitoring & Outcome in KEM Hospital, Mumbai. American Journal of Epidemiology and Infectious Disease. 2014; 2(4):97-100. doi: 10.12691/ajeid-2-4-3

Abstract

Dengue is the most important vector-borne viral disease of humans and likely more important than malaria globally in terms of morbidity and economic impact [8]. Transmission of dengue is now present in every region of the world and more than 125 countries are known to be dengue endemic. Maharashtra has the highest dengue mortality rate (3.4%) in India, as per data obtained from National Vector Borne Diseases Control Program (NVBDCP-2013). The case fatality rate is significantly high as compared that with other infectious diseases. This observational study was done to obtain the information on treatment given & its outcome in clinical profile & also to assess treatment gap & outcome of Dengue patients admitted in KEM Hospital. The data was collected from the case records of dengue diagnosed patients from Medical record department and it was filled in case record form. The statistical-analysis & the conclusion were drawn with the help of observations. The study revealed that maximum number (121) of dengue cases were in the age group of 21-30 yrs. There was an association between platelet count and treatment outcome. Severity in sign & symptoms lead to complication (n=23) and death (n= 21) in dengue cases. There were 22 deaths occurred in year 2013 because of dengue. Out of which maximum 12 cases reported in months of September (n=6) & October (n=6). There was no treatment gap found in cases of Deaths in study but 36% of died patients received antimalarial treatment even after diagnosed with Dengue. Remaining 64% of died patients received appropriate, rational and life saving treatment for dengue.

Keywords:
dengue cases treatment monitoring treatment outcome treatment gap

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References:

[1]  Agarwal, R, Kapoor, S, Nagar, R, & et al. “A clinical study of the patients with dengue hemorrhagic fever during the epidemic of 1996 at Lucknow, India.” Southeast Asian J Trop Med Public Health; 30: 735-40. 1999.
 
[2]  Ahmed, MM and et al, “Clinical profile of dengue fever infection in King Abdul Aziz University Hospital Saudi Arabia.” J Infect Dev Ctries 3; 4 (8): 503-10, Sept. 2010.
 
[3]  Alves, JA, Santos, JR, Mendonca, EN, “Epidemiological aspects of dengue in Aracaju, State of Sergipe, Brazil.” Rev Soc Bras Med Trop. 44 (6):670-3, Nov-Dec 2011.
 
[4]  Anderson, CR, Downs, WG, & Hill, AE. “Isolation of dengue virus from a human being in Trinidad. Science.” 124 (3214): 224-5,1956. [PubMed]
 
[5]  Arboleda, M, Campuzano, M, Restrepo, BN, & et.al, “The clinical behavior of dengue in patients hospitalized in the Antonio Roldán Betancur Hospital of Apartadó, Antioquia, 2000.” Emerg Infect Dis. 13 (6):924-5, June2007.
 
[6]  Aung, KL, Thanachartwet, V, & Desakorn, V, “Factors associated with severe clinical manifestation of dengue among adults in Thailand.” Biomedica ; 26 (2): 286-94. Jun. 2006.
 
[7]  Balmaseda, A, Hammond, SN, Tellez, Y, Imhoff, L, Rodriguez, Y, Saborio, SI, & et al. “High seroprevalence of antibodies against dengue virus in a prospective study of schoolchildren in Managua,Nicaragua.” Trop Med. Int Health; 11: 935-42. 10. 2006 [PubMed]
 
[8]  Bhattacharjee, N, Mukherjee, KK, Chakravarti, SK, Mukherjee, MK, & et al. “Dengue haemorrhagic fever (DHF) outbreak in Calcutta-1990.” J Commun Dis.; 25: 10-4, 1993.
 
[9]  Brasil. Ministério da Saúde. Secretaria de Vigilância em Saúde Dengue: diagnóstico e manejo clínico. 2nd ed Brasília, DF; 2005.
 
[10]  Carey, DE, Myers, RM, Reuben, R, & Rodrigues, FM, “Studies on dengue in Vellore, South India.” Am J Trop Med Hyg.; 15: 580-7, 1966.
 
[11]  Chambers, TJ, Hahn, CS, Galler, R, & Rice, CM. “Flavivirus genome organization, expression, and replication.” Annu Rev Microbiol.; 44: 649-88, 1990. [PubMed]
 
[12]  Chatterjee, SN, Chakravarti, SK, Mitra, AC, & Sarkar, JK, “Virological investigation of cases with neurological complications during the outbreak of haemorrhagic fever in Calcutta.” J Indian Med Assoc.; 45: 314-6, 1965.
 
[13]  Cherian, T, Ponnuraj, E, Kuruvilla, T, & et.al, “An epidemic of dengue haemorrhagic fever & dengue shock syndrome in & around Vellore.” Indian J Med Res.; 100: 51-6, 1994.
 
[14]  Chuang, V, Wong, TY, Leung, YH, “Review of dengue fever cases in Hong Kong during 1998 to 2005.” Hong Kong Med J.; 14 (3): 170-7, Jun.2008.
 
[15]  Dar, L, Broor, S, Sengupta, S, Xess, I, & Seth, P, “The first major outbreak of dengue hemorrhagic fever in Delhi, India.” Emerg Infect Dis.; 5: 589-90, 1999.
 
[16]  Faddy, HM, Seed, CR, Fryk, JJ, “Implications of dengue outbreaks for bloodsupply, Australia .” Emerg.Infect.Dis.; 19 (5): 787-9, May. 2013.
 
[17]  Gunasekaran, P, Kaveri, K, Mohan, S. “Dengue disease status in Chennai (2006-2008): a retrospective analysis.” Indian J Med Res.; 133: 322-5, Mar. 2011.
 
[18]  Kabra, SK, Verma, IC, Arora, NK, & et.al, “Dengue haemorrhagic fever in children in Delhi.” Bull World Health Organ.; 70:105-8, 1992.
 
[19]  Katherine, L. Anders, & et.al, “Epidemiological factors associated with DSS & mortality in hospitalized Dengue patients in Vietnam.” Am J Trop Med Hyg. 5; 84 (1): 127-134. January 2011.
 
[20]  Khursheed, M, Khan, UR, & Ejaz, K, “A comparison of WHO guidelines issued in 1997 and 2009 for dengue fever-single centre experience.” J Pak Med Assoc.; 63 (6): 770-1, Jun. 2013.
 
[21]  Kimura, R, & Hotta, S, “Studies on dengue fever (IV) on inoculation of dengue virus into mice.” Nippon Igaku.; 3379: 629-33, 1944.