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American Journal of Biomedical Research
ISSN (Print): 2328-3947 ISSN (Online): 2328-3955 Website: https://www.sciepub.com/journal/ajbr Editor-in-chief: Hari K. Koul
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Issue 2, Volume 12
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American Journal of Biomedical Research. 2024, 12(2), 11-15
DOI: 10.12691/ajbr-12-2-1
Open AccessReview Article

Do Antimicrobial Resistance and Virulence Share Same Genetic Elements

Zangini Nakazwe1, and Chipampe Lombe1

1Department of Basic Sciences, University of Lusaka, P.O Box 36711, Lusaka, Zambia

Pub. Date: April 11, 2024
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Cite this paper:
Zangini Nakazwe and Chipampe Lombe. Do Antimicrobial Resistance and Virulence Share Same Genetic Elements. American Journal of Biomedical Research. 2024; 12(2):11-15. doi: 10.12691/ajbr-12-2-1

Abstract

Antimicrobial resistance (AMR) is a growing global health challenge with increased health care costs, mortality and morbidity. Over the years, microbes of clinical importance have coevolved with their hosts and have developed virulence mechanisms through mutations and horizontal gene transfer in order to compete and withstand hash environmental conditions including those posed by antimicrobial agents. Antimicrobial resistance and virulence mechanisms promote survival of microorganisms in their hosts. Several research studies have shown putative association between antimicrobial resistance and virulence but overlooked genetic link between the two. This review focuses on establishing whether antimicrobial resistance and virulence share the same genetic elements.

Keywords:
Antimicrobial resistance virulence AIEC gene profile

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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