Anthelmintic Activities of Polypodium Decumanum Leaf-Extracts

Pawan Sharma¹, Chhater Singh^2, and Rohit Saraswat¹

¹OPJS University, Churu, Rajasthan

²Department of Pharmacy, Dron College of Education Meerut

Cite this paper:
Pawan Sharma, Chhater Singh and Rohit Saraswat. Anthelmintic Activities of Polypodium Decumanum Leaf-Extracts. American Journal of Biomedical Research. 2021; 9(1):1-4. doi: 10.12691/ajbr-9-1-1

Abstract

Various herbal plants used in traditional medicines contain a vast array of substances that can be used to treat various disease and complications, the present study deals with anthelmintic activity of different extracts of leaves of Polypodium decumanum, a potential medicinal plant. The crude plant extracts of leaf part exhibited anthelmintic activity. Two concentrations (30mg/ml and 40mg/ml) of each extract were studied, which involved for the determination of time of paralysis and time of death of the test worms. It was found that ethyl acetate extracts exhibited significant anthelmintic activity followed by ethanolic extract and aqueous extract in causing paralysis and death of earth worms.

Keywords:
Polypodiun decumanum anthelmintic activity piperazine citrate

This work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References:

[1]	Agaie, B.M., Onyeyili, P.A., Bundy, Anthelmintic activity of crude aqueous leaf of Anogeissus leiocarpus in sheep. African J. of Biotechnology, 1994, 6, 1511-1515.
[2]	Chandrashekhar, C.H., Latha, K.P., Vagdevi, H.M., Vaidya, V.P., Kosalge, Anthelmintic activity of the crude extracts of Ficus racemosa. Int. J. of Green Pharmacy. 2009, 103.
[3]	Raina, M.K., Quality control of herbal and herbo-mineral formulations. Indian Journal of Natural Products, 2003, 19, 11-15
[4]	Aswar, M., Aswar, U., Watkar, B., Vyas, M., Wagh, A., Gujar, K.N., Anthelmintic activity of Ficus benghalensis. Int. J. of Green Pharmacy. 2008, 170-172.
[5]	Mukerjee, P.K., Quality control of Herbal drugs: An approach to evaluation of botanicals, 1st ed, Bussiness Horizons, New Delhi, 2002.
[6]	Bundy, D.A., Immunoepidemiology of intestinal helminthic infection I: the global burden of intestinal nematode disease. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1994, 8, 259-261.
[7]	Berti G., Bottari P., Marsili A., Morelli I., A triterpenoid epoxide from polypodium vulgare. Tetrahedron Letters. 1966, 7 (9), 979-982.
[8]	Herfindal and Gourley, 2000. Textbook of Therapeutics: Drug and Disease Management, 6th Edition, Lippincott Williams & Wilkins. 305-323.
[9]	B Bibhilesh; Mendhe; Umesh Nema; Piyush Gupta; R Bhushan. Inter J Pharm Sci and Res., 2010, 1(3): 69-72.
[10]	EO Ajaiyeoba; PA Onocha; OT Olarenwaju. Pharm Biol., 2001, 39: 217-20.
[11]	V Suresh; G Arunachalam; N Senthil Kumar. J.Pharmy Res., 2011, 4(1): 283-284.
[12]	RD Vidyarthi. A textbook of Zoology. Chand S and Co, New Delhi, 14thed, 1967.
[13]	KD Chatterjee. Parasitology, Protozoology and Helminthology. In Guha Ray Sree Saraswaty Press Ltd,Calcutta, 6thed, 1967.
[14]	T Sollmann. J Pharmacol. Exp. Ther., 1918, 12: 120-70.