Applied Ecology and Environmental Sciences
ISSN (Print): 2328-3912 ISSN (Online): 2328-3920 Website: Editor-in-chief: Alejandro González Medina
Open Access
Journal Browser
Applied Ecology and Environmental Sciences. 2020, 8(4), 174-178
DOI: 10.12691/aees-8-4-5
Open AccessArticle

Enviro-economic Synthesis, Characterization and Antibacterial Study of O-Alkyl or O-Aryl Trithiophosphates of Cadmium

Kamiya Mundra1 and Alok Chaturvedi1,

1Synthetic and Surface Science Laboratory, Department of Chemistry, S.P.C. Govt. College, Ajmer 305001, Rajasthan, India

Pub. Date: June 08, 2020

Cite this paper:
Kamiya Mundra and Alok Chaturvedi. Enviro-economic Synthesis, Characterization and Antibacterial Study of O-Alkyl or O-Aryl Trithiophosphates of Cadmium. Applied Ecology and Environmental Sciences. 2020; 8(4):174-178. doi: 10.12691/aees-8-4-5


Cadmium (II) O-alkyl or O-aryl trithiophosphate of the type Cd[KS(S2)POR]2 (where R= Me, Et, Pri, Bui, Ph, CH2Ph) have been synthesized by an environmentally harmless, efficient and quick smooth way from the reaction of cadmium chloride and dipotassium salt of O-alkyl or O-aryl trithiophosphates in 1:2 molar ratio. They are synthesized by solvent free conditions and microwave assisted procedure. These derivatives are yellow colour solids, insoluble in common organic solvents but are soluble in DMSO, DMF and pyridine. These have been characterized by elemental analysis, molecular weight determinations and spectroscopic(IR, 1H and 31P NMR) studies. On the basis of them square planar geometry has been proposed for these derivatives. The newly synthesized complexes show effectiveness against gram positive and gram negative bacteria and a comparative study of antibacterial effect of synthesized compounds with standard drugs has also been investigated.

cadmium chloride dipotassium salts of O-alkyl or O-aryl trithiophosphates solvent free conditions microwave assisted procedure antibacterial activity

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit


[1]  A. Chaturvedi, R. K. Sharma, P. N. Nagar and A. K. Rai; Phosphorous, Sulfur and Silicon.; 112, 179 (1996).
[2]  R. Purwar, M. K. Sharma, R. K. Sharma and P. N. Nagar; Phosphorous, Sulfur and Silicon.; 174, 15 (2001).
[3]  C. S. Sharma, M. K. Sharma, R. K. Sharma, and P. N. Nagar; Phosphorous, Sulfur and Silicon.; 1, 177 (2002).
[4]  U. N. Tripathi, D. K. Sharma, N. Jain and H. Soni; Phosphorous, Sulfur and Silicon.; 182(7), 1033 (2007) .
[5]  C. Habig, G. DJ and T. Richard; Mar. Environ. Res, 24 (1-4), 193,(1988), Chem. Abstr.; 109, 49948V (1988).
[6]  B. Krzyzanowska and W. J. Stec; Phosphorous and Sulfur.1987, 30 (1-2), 287, Chem. Abstr.; 108, 131929F(1988).
[7]  G.V. Dave and P.J. Vyas; Journal of Current Chemical &Pharmaceutical Sciences.; 2, 133-148 (2012).
[8]  A.L. Bingham, J.E. Drake, M.B. Hursthouse, M.E. Light, M. Nirwan and R. Ratnani; Polyhedron.; 26, 2672-2678 (2007).
[9]  S. Maheshwari, J.E. Drake, K. Kori, M.E. Light and R. Ratnani; Polyhedron; 28, 689-694 (2009).
[10]  A. A. El Khaldy, A.R. Hussien, A.M. Abushanab and M.A. Wasse; Phosphorus Sulfur and Silicon Relat. Elem ; 186, 589-597, (2011).
[11]  A.M. Cotero-Villegas, R.A. Toscano and M. Munoz; Journal Of Organometallic Chemistry; 690, 2872-2879 (2005).
[12]  N. Ma, Y. Li, H. Xu, Z. Wang, and X. Zhang; Journal Of the American Chemical Society; 132, 442-443 (2010).
[13]  R. Z. Kowalsk, N. A. Bailey, R. Mulvany, H. Adams, D. A. O. Gleirigh and J. A. McCleverty, Transition Met. Chem.; 6, 64 (1981).
[14]  S. L. Lawton and G. T. Kokatailo, Inorg. Chem., 8, 2410 (1969).
[15]  J. A. Howard, Y. Ohkatsu, J. H. B. Chemien and K. V. Ingold, Can. J. Chem.; 51, 1543 (1973).
[16]  C. Habig, G. DJ and T. Richard., The anticholinesterase effect of the cotton Defoliant S,S,S –tri-nbutyl Phosphorotrithioate (DEF) on Channel Catfish, Mar. Environ. Res. 24 (1-4), 193-197, (1988). Chem. Abstr.; 109, 49948V (1988).
[17]  A. Chaturvedi, C. S. Sharma, P. N. Nagar, Phosphorus Sulfur and Silicon; 178:1923 (2003).
[18]  L. Chordia, A. Chaturvedi. Phosphorus Sulfur and Silicon; 182:2821 (2007).
[19]  S. Shahzad, K. Shafrid, S. Ai. M. Mazhar and K. M. Khan, J. Iran. Chem. Soc.; 2(4), 277-288 (2005).
[20]  U. N. Tripathi, A. Siddiqui, Mohd. Safi, Nitya Sharma and Neetu Shrivastava; Phosphorus Sulfur and Silicon; 185, 1993, (2010).
[21]  U. N. Tripathi and D. K. Sharma; Phosphorus Sulfur and Silicon; 180, 1559 (2005).
[22]  U. N. Tripathi, Mohd. Ahmad; Phosphorus Sulfur and Silicon; 179(11), 2307 (2004).
[23]  J. Martin Gill, F. J. Martin Gill, M. Jose Yacaman, L. Carakia Marales, and T. Falcon -Barcenas; Polish J. Chem. 1399 (2xq005).
[24]  K. J. Rao, B. Vaidhyanathan, M. Ganduli and P. A. Ramakrishnan; Chem. Mater. 11, 882 (1999).
[25]  K. Zhao and W. Yan; Modern inorganic synthesis chemistry. Chapter 8, 173. (2011).
[26]  R. Hekmatshoar, M. M. Heravi, B. Baghernejad, and K. Asadolah; Phosphorus Sulfur and Silicon. 179, 1611 (2004).
[27]  A. Chaturvedi, Bharti Chaturvedi; International Journal of Recent Scientific Research; 8(9), 20235-20237 (2017).
[28]  A. Chaturvedi, Mahendra Kumar Rana; International Journal of Recent Scientific Research; 8(9), 19894-19896 (2017).
[29]  A. Chaturvedi, Suman Bhatti; International Journal of Recent Research Aspects; 4(3), 183-187 (2017).
[30]  B. P. Kotavich, N. I. Zemlyanskii, I. V. Mwzavev and M. P. Volosin; Zn. Obsch. Khim; 38(6), 1282 (1968).
[31]  A. I. Vogel, "A Text Book of Quantitative Inorganic Analysis" Longman E.L.B.S. IV Edition (1973).
[32]  D. E. C. Corbridge, “Topics in Phosphorus Chemistry,” 6, 235 (1969).
[33]  P. G. Harrison, H. J. Bagley and T. Kikabhai, J. Chem. Soc., Dalton Trans., 925, 929 (1986).