Mariana Piana^1,, Roberta da silva Jesus¹, Aline Augusti Boligon¹, Sílvio Terra Stefanello², Thiele Faccim de Brum¹, Camilla Filippi dos Santos Alves¹, Natalia Jank Mossmann¹, Bianca Vargas Belke¹, Félix Alexandre Antunes Soares², Sara Marchesan de Oliveira³, Liliane de Freitas Bauermann¹

The antioxidant activity and phenolic compounds of the chloroform (CHCl₃), ethyl acetate (AcOEt) and n-butanol (n-BuOH) fractions from Solanum corymbiflorum leaves and fruits were evaluated. The AcOEt fraction of the leaves presented the highest content of total polyphenols (114.00 mg GAE/g) and the best antioxidant capacity by 1,1-diphenyl-2-picrylhydrazyl (DPPH) test (IC₅₀ = 31.90 µg/mL). For the fruits, the same fraction exhibited the highest content of phenolics (99.77 mg GAE/g) and best results in the DPPH test (IC₅₀ = 141.47 µg/mL). In relation to 2′,7′-dichlorofluorescein diacetate (DCFH-DA) and thiobarbituric acid reactive substances (TBARS) assays, the CHCl₃ fraction of leaves and fruits showed better results than the other samples analyzed. Besides of the phenolic compounds, the alkaloids contributed in the activity. Rutin, chlorogenic and caffeic acids quantified by HPLC are some of phenolic compounds responsible by this activity S. corymbiflorum can be a promising source of natural antioxidants. However, more in vivo studies are required to stimulate the consumption and its other potentialities.

Solanum corymbiflorum, antioxidant activity, HPLC, chlorogenic acid, Cyphomandra corymbiflora