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Reyes-Farias, M., Vasquez, K., Ovalle-Marin, A., Fuentes, F., Parra, C., Quitral, V., Jimenez, P. and Garcia-Diaz, D.F., “Chilean native fruit extracts inhibit inflammation linked to the pathogenic interaction between adipocytes and macrophages,” Journal of Medicinal Food, 18 (5). 601-608. May 2015.

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Article

Effect of Multi-berries Drink on Endogenous Antioxidant Activity in Subjects Who Are Regular Smokers or Drinkers

1Department of Recreational Sport and Health Promotion, National Pingtung University of Science and Technology, Pingtung, Taiwan

2Department of Biological Science and Technology, National Chiao Tung University, Hsinchu, Taiwan

3Research & Design Center, TCI Co., Ltd., Taipei, Taiwan


Journal of Food and Nutrition Research. 2016, Vol. 4 No. 5, 289-295
DOI: 10.12691/jfnr-4-5-4
Copyright © 2016 Science and Education Publishing

Cite this paper:
Bo-Han Wu, Wen-Chao Wang, Hsin-Yu Kuo. Effect of Multi-berries Drink on Endogenous Antioxidant Activity in Subjects Who Are Regular Smokers or Drinkers. Journal of Food and Nutrition Research. 2016; 4(5):289-295. doi: 10.12691/jfnr-4-5-4.

Correspondence to: Hsin-Yu  Kuo, Research & Design Center, TCI Co., Ltd., Taipei, Taiwan. Email: sophie.kuo@tci-bio.com

Abstract

The multi-berries drink (MBD) has been demonstrated to possess high total polyphenol content and antioxidant activity measuring by ORAC and CAA assays. The influence of MBD supplement on endogenous antioxidant activity in healthy subjects was evaluated in this study. Twenty adults who smoke or drink alcohol regularly were allocated to MBD (100 mL/d, n = 10) or the control (placebo, 100 mL/d, n = 10) group for a 90-day, randomized, double-blind, placebo-controlled study. The results showed that MBD supplementation significantly increased glutathione (GSH), the activities of glutathione peroxidase (GSH-Px), glutathione reductase (GSH-Rd), superoxide dismutase (SOD) and decreased thiobarbituric acid reactive substances (TBARS) compared with the placebo. Additionally, hepatic and renal functions were not adversely altered in MBD-ingested subjects. It is suggested that MBD effectively promotes the endogenous antioxidant activity, and can be consumed as a functional supplement for people who are in danger of suffering oxidative-related chronic diseases.

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