Meltem Yaman Onmus^1,, Elif Cakirca Avcu¹, Ali Saklamaz¹

Obesity is caused by the chronic low-level inflammation of white adipose tissue associated with the activation of the immune system. Food intolerance (FI) is one of the probable cause of this low-level inflammation. Food intolerance test had been done to the patients who were refractory to lose weight. In this study, we tried to prove that the elimination diet, based on test results, can help with weight loss in patients. 82 patients were enrolled in the study. Their ages were between 18-65 years and had BMI ≥ 25 kg / m². The FI test was done to all of them. The patients randomized to control or FI groups. The FI group was given food intolerance elimination diet (FIED) while the patients in the control group underwent a weight loss program by supervision of a dietitian. The patient’s body weight, fat weight, lean body mass, body mass index, waist/hip ratio were measured before and after the diet program of the two groups. At the same time, fasting blood sugar, lipid and A1c levels were tested. In the FI group, patients significantly lost weight 86.60±20.93 kg (BMI=31.40±4.68 kg/m²) to 77.99±14.23 kg (BMI=28.95±4.23 kg/m²) (p<0.05). In the control group the body weight also decreased from 89.60±17.69 kg (BKI= 33.09±4.70 kg/m²) to 88.69±18.44 kg (BKI= 32.44±5.09 kg/m²) (p<0.05). Body fat weight decreased from 32.22±8.18 kg to 27.00±8.27 kg in the FI group while in the control group it was decreased from 36.18±10.50 kg to 36.17±12.76 kg (p<0.05). Triglyceride levels of the FI group decreased significantly than the control group (p<0.05). There was no significant change in fasting blood glucose, A1c and cholesterol levels of two groups at the end of study (p>0.05). In this study, people who cannot lose weight by low-calorie diet can lose weight and fat with elimination diet according to the results of FI test. FIED is also significantly effective in triglyceride levels.

food intolerance, obesity, elimination diet