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Jiang BP, Le L, Wan WT, Zhai W, Hu KP, Xu LJ, Xiao PG. The flower tea coreopsis tinctoria increases insulin sensitivity and regulates hepatic metabolism in rats fed a high-fat diet. Endocrinology, 2015; 156(6), 2006-2018.

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Article

Free Radical-scavenging, Nitrite-scavenging, and N-nitrosamine Formation Inhibitory Activities of Extracts from Kunlun Compositae Tea (Coreopsis tinctoria Nutt.)

1School of Pharmacy, Shihezi University, Shihezi, Xinjiang, P.R.China

2Key Laboratory of Xinjiang Endemic Phytomedicine Resources, Ministry of Education, Shihezi University, Shihezi, Xinjiang, P.R.China


Journal of Food and Nutrition Research. 2015, Vol. 3 No. 9, 587-592
DOI: 10.12691/jfnr-3-9-5
Copyright © 2015 Science and Education Publishing

Cite this paper:
Xincheng Yao, Ting Zhang, Hui Tang, Heng Wang, Wen Chen. Free Radical-scavenging, Nitrite-scavenging, and N-nitrosamine Formation Inhibitory Activities of Extracts from Kunlun Compositae Tea (Coreopsis tinctoria Nutt.). Journal of Food and Nutrition Research. 2015; 3(9):587-592. doi: 10.12691/jfnr-3-9-5.

Correspondence to: Hui  Tang, School of Pharmacy, Shihezi University, Shihezi, Xinjiang, P.R.China. Email: th_pha@shzu.edu.cn

Abstract

Coreopsis tinctoria Nutt., Asteraceae, is widely used as an ornamental plant and as a popular tea production in China. In this paper, we report about the free radical-scavenging, nitrite-scavenging and N-nitrosamine formation inhibitory activities of ethyl acetate extract (EAE) and n-butanol extract (BE) of C. tinctoria flowering tops (CTF). The results showed the BE contained higher total phenolic content (TPC) , total flavonoid content (TFC) and total proanthocyanidin (TPA) contents with DPPH, ABTS and *OH radical-scavenging activities (IC50) of 25.79±2.753, 26.61±3.158 and 2349.8±0.672 μg/ml, respectively. However, EAE showed higher radical-scavenging activities, with IC50 ABTS and *OH values of 13.71±2.973 and 321.6±0.576 μg/ml, respectively. The nitrite-scavenging and N-nitrosamine inhibitory activities (IC50) of EAE were 122.10±1.03 and 2362.86±11.26 μg/ml, respectively, whereas those of BE were 118.23±1.30 and 2182.79±10.74 μg/ml, respectively. Given these activities, we propose that CTF can be potentially used as a rich source of natural free radical and nitrite scavengers.

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