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Liel Y, Harman-Boehm I, Shany S. Evidence for a clinically important adverse effect of fiber-enriched diet on the bioavailability of levothyroxine in adult hypothyroid patients. J Clin Endocrinol Metab 1996; 81: 857-859.

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Article

Clinical Application of the Levothyroxine Absorption Test in the Diagnosis of Pseudo-Malabsorption

1Department of Diabetes and Endocrinology, Peterborough City Hospital, Peterborough, UK

2Department of Diabetes and Endocrinology, Weston General Hospital, Weston-super-Mare, UK

3Department of Diabetes and Endocrinology, Hereford County Hospital, Hereford, UK


American Journal of Medical Case Reports. 2014, Vol. 2 No. 11, 253-255
DOI: 10.12691/ajmcr-2-11-8
Copyright © 2014 Science and Education Publishing

Cite this paper:
Muhammad Imran Butt, Nidhi Gupta, Hiang Leng Tan, Najeeb Waheed. Clinical Application of the Levothyroxine Absorption Test in the Diagnosis of Pseudo-Malabsorption. American Journal of Medical Case Reports. 2014; 2(11):253-255. doi: 10.12691/ajmcr-2-11-8.

Correspondence to: Hiang  Leng Tan, Department of Diabetes and Endocrinology, Weston General Hospital, Weston-super-Mare, UK. Email: hiangleng@doctors.org.uk

Abstract

We present a variation and clinical application of the Levothyroxine Absorption Test (LAT) in the identification of pseudo-malabsorption of levothyroxine in uncontrolled hypothyroidism, for which there is no current gold standard protocol, and a variety of methods proposed in the literature. The LAT was conducted over 5-days with thyroid function tests conducted pre-LAT, then at day 1 and 5. The thyroid stimulating hormone levels became completely suppressed indicating that there had been previous non-compliance with medication.

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