1Clinic of Gastroenterology, Clinical Center of Gastroenterology, University Hospital “Queen Joanna”, Sofia, Bulgaria
2Department of Radiology, University Hospital “Queen Joanna”, Sofia, Bulgaria
3Clinic of Abdominal Surgery, Clinical Center of Gastroenterology, University Hospital “Queen Joanna”, Sofia, Bulgaria
4Department of Pathology, University Hospital “Queen Joanna”, Sofia, Bulgaria
International Journal of Celiac Disease.
2016,
Vol. 4 No. 1, 30-33
DOI: 10.12691/ijcd-4-1-8
Copyright © 2016 Science and Education PublishingCite this paper: Ludmila Tankova, Vanya Gerova, Plamen Getsov, Nikolay Penkov, Gergana Taneva, Ivan Terziev, Radislav Nakov. The Association of Crohn’s Disease, Celiac Disease and Selective Ig A Deficiency.
International Journal of Celiac Disease. 2016; 4(1):30-33. doi: 10.12691/ijcd-4-1-8.
Correspondence to: Radislav Nakov, Clinic of Gastroenterology, Clinical Center of Gastroenterology, University Hospital “Queen Joanna”, Sofia, Bulgaria. Email:
radislav.nakov@gmail.comAbstract
Concomitant occurrence of celiac disease (CeD) and Crohn’s disease (CD) is rare and has been reported in several case reports and series. We report a case of a 63-year-old man with proximal CD, CeD and selective immunoglobulin (Ig) A deficiency (SIgAD). The patient was admitted in our Clinic for evaluation of epigastric pain, nausea, vomiting and weight loss (up to 7 kg) appeared in the last 3 months. The imaging findings from abdominal ultrasound and CT enterography raised suspicion of a lymphoproliferative disease of the jejunum. To exclude the development of lymphoma based on long standing untreated atypical CeD, upper endoscopy with biopsies and serological tests were conducted, showing and subtotal villous atrophy and elevated levels of IgG tissue transglutaminase tTG. Histopathology documented CD (A3,L4,B2 according to Montreal’s classification).
Keywords