Sidhartha Sankar Sahoo^1,, Malaya Kumar Hota¹

Proteins perform their functions by interaction with other molecules known as target. Protein-target interactions are very specific in nature and occur at predefined locations in proteins known as hotspots. For successful protein-target interaction both protein and target must share common spectral component known as characteristic frequency. Characteristic frequency is very importance since it forms basis for protein-target interactions, thus far various computational simulations have been used for determination of characteristics frequency. In this paper we have applied all computational simulations used till now and also use comparative study based on computational time and Signal to Noise Ratio parameter to stress the best suitable technique. All computational simulation works in this paper are done using MATLAB.

proteins, amino acids, Electron Ion Interaction Potential (EIIP), consensus spectrum, resonant recognition model (RRM), characteristic frequency, Discrete Fourier Transform (DFT), Chirp Z-Transform (CZT), Discrete Cosine Transform (DCT)