Leilei Yu^{1, 2}, Peifeng Li^{1, 2,}

Bacterial infections caused by the misuse of antibiotics have gradually become a growing global problem. Highly toxic reactive oxygen species (ROS) are an ideal means of efficient and rapid sterilization, resulting in the leakage of bacterial contents by destroying bacterial membranes. In this study, we are to develop highly efficient Au@Pd nanospheres with peroxidase activity as antibacterial nanomaterials. The classical TMB chromogenic experiment showed that Au@Pd nanospheres had good peroxidase activity to produce ROS and achieve the antibacterial effect. Bacterial experiments have shown that Au@Pd nanospheres with peroxidase activity have great potential in inhibiting Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus).

bacterial infections, peroxidase