Sebastian Alberto Ramos-Arcos¹, Sugey López-Martínez^1,, José R. Velázquez-Martínez², Yenny A. Gómez-Aguirre³, Emmanuel Cabañas-García⁴, Carlos M. Morales-Bautista⁵, Minerva A. Hernandez-Gallegos⁶

Research was conducted on the biological potential and phenolic composition of Tradescantia zebrina Bosse. Through aqueous and hydroalcoholic extracts of leaves of the species, the total phenolic content (TPC), total flavonoid content (TFC) and total tannin content (TTC) were determined; the antioxidant activity by DPPH•, ABTS•+ and FRAP methods, as well as the biological activities, antibacterial by agar diffusion and minimum inhibitory concentration (MIC), and anti-inflammatory under the 12-O-tetradecanoylphorbol-13-acetate (TPA) method in Institute of Cancer Research (ICR) mice. The hydroalcoholic extract presented the highest TPC (73.07 ± 0.78 mg EAG/g), TFC (24.34 ± 0.68 mg EC/g) and TTC (26.96 ± 0.18 mg EAG/g), and a relevant antioxidant activity with the FRAP assay (353.92 ± 3.20 mM ET/g). In addition, this extract was the only one that presented an inhibition zone of 8.5 ± 1.4 and 8 ± 0.0 mm, against Bacillus cereus and Staphylococcus aureus, respectively. As well as a higher percentage of inhibition of inflammation (47.99%), an approximate value to the reference drug used. The evidence indicates that this plant possessing pharmaceutical potential that can be further explored as a natural source of new drugs.

Tradescantia zebrina, antioxidant, antibacterial, anti-inflammatory, extracts