Sana Noreen¹, Rabia Kanwal¹, Abdul Rehman², Ayesha Sadiqa³, Fizza Mubarak¹, Madiha Khan Niazi¹, Ahasan Ullah Khan^{4, 5}, Yunita Sari Pane^6,

The current study aims to assess the impact of obesity on polycystic ovary syndrome. It has a huge impact on the body, impacting physical, emotional, cognitive, and intellectual faculties. Diabetes mellitus, cardiovascular disease, endometrial cancer, and other clinical problems result. Insulin resistance, which refers to the process by which the body is unable to respond to insulin production sequentially, leading to a high level of triglycerides and cholesterol in the blood, is one of the most dangerous aspects studied in these individuals. Obesity is the leading cause of this condition, which is caused by an excessive buildup of fat in the body, which interferes with the body's natural functioning. Cardiovascular illnesses, which lead to a higher death rate globally, have a substantial relationship with PCOS. Women with PCOS have an increased amount of fatty tissues, which can worsen the condition and lead to type-II diabetes, stroke, and CVD. Physical manifestations of this heinous disease include acne, hirsutism, androgenetic alopecia, or male pattern baldness. Metabolic abnormalities contribute to the development and progression of PCOS and have major ramifications in later life that can be hazardous to health. It has been shown that even a 5% weight loss can reduce insulin and testosterone levels and improve fertility and menstrual cycle. Cinnamon has been shown to enhance menstrual cyclicity and insulin sensitivity in women with PCO. The purpose of this review is to investigate the efficacy of cinnamon supplementation in conjunction with specific lifestyle modifications, which has been proven to have potential therapeutic benefits against obesity and PCOS.

hormonal issues, non-communicable diseases, Cinnamon