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Osawa Y, Mizushige T, Jinno S, Sugihara F, Inoue N, Tanaka H, et al. Absorption and metabolism of orally administered collagen hydrolysates evaluated by the vascularly perfused rat intestine and liver in situ. Biomed Res. 2018; 39: 1-11.

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Article

Novel Hydrolyzed Porcine and Fish Collagen Beverage Improved Collagen, Elasticity, Moisture, Spots: A Randomized, Double-blind, Placebo-controlled Trial

1Institute of Food Safety and Risk Management, National Taiwan Ocean University, Keelung, Taiwan

2Department of Food Science, National Taiwan Ocean University, Keelung, Taiwan;Graduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung, Taiwan

3Department of Cosmetic Science and Institute of Cosmetic Science, Chia Nan University of Pharmacy and Science, Tainan, Taiwan

4Research & Design Center, TCI CO., Ltd., Taipei, Taiwan


Journal of Food and Nutrition Research. 2022, Vol. 10 No. 4, 305-312
DOI: 10.12691/jfnr-10-4-7
Copyright © 2022 Science and Education Publishing

Cite this paper:
Yung-Kai Lin, Chia-Hua Liang, Yung-Hsiang Lin, Shu-Ting Chan, Chi-Fu Chiang. Novel Hydrolyzed Porcine and Fish Collagen Beverage Improved Collagen, Elasticity, Moisture, Spots: A Randomized, Double-blind, Placebo-controlled Trial. Journal of Food and Nutrition Research. 2022; 10(4):305-312. doi: 10.12691/jfnr-10-4-7.

Correspondence to: Chi-Fu  Chiang, Research & Design Center, TCI CO., Ltd., Taipei, Taiwan. Email: Jimmy.Chiang@tci-bio.com

Abstract

Background: As the population ages, oral hydrolyzed collagen supplements are gaining traction. However, few clinical studies on the skin health of hydrolyzed porcine collagen combined with fish collagen. Objective: This study investigates whether TripleUp collagen beverage has skincare and anti-inflammatory effects. Methods: Using collagen beverage to treat epidermal keratinocytes and examine ROS, HA, inflammatory factor, and moisturizing-related gene expressions (Tgm1, Krt14, FLG-F, GBA, HAS3). Fifty subjects were recruited into a placebo and collagen beverage group for four weeks and then examined skin condition at 0, 2, 4 weeks. Results: TripleUp collagen beverage decreased IL-8 and ROS expression and increased moisturizing-related gene expressions. In addition, collagen beverages increase skin collagen, elasticity, moisture, and decreased spots. Conclusions: Thus, TripleUp collagen beverage included hydrolyzed porcine, and fish collagen and vitamin C can improve skin condition.

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