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D'Orazio J, Jarrett S, Amaro-Ortiz A, Scott T. UV radiation and the skin. Int J Mol Sci. 2013; 14: 12222-48.

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Article

Novel Hydrolyzed Porcine and Fish Collagen Beverage Improved Collagen, Elasticity, Moisture, Spots: A Randomized, Double-blind, Placebo-controlled Trial

1Institute of Food Safety and Risk Management, National Taiwan Ocean University, Keelung, Taiwan

2Department of Food Science, National Taiwan Ocean University, Keelung, Taiwan;Graduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung, Taiwan

3Department of Cosmetic Science and Institute of Cosmetic Science, Chia Nan University of Pharmacy and Science, Tainan, Taiwan

4Research & Design Center, TCI CO., Ltd., Taipei, Taiwan


Journal of Food and Nutrition Research. 2022, Vol. 10 No. 4, 305-312
DOI: 10.12691/jfnr-10-4-7
Copyright © 2022 Science and Education Publishing

Cite this paper:
Yung-Kai Lin, Chia-Hua Liang, Yung-Hsiang Lin, Shu-Ting Chan, Chi-Fu Chiang. Novel Hydrolyzed Porcine and Fish Collagen Beverage Improved Collagen, Elasticity, Moisture, Spots: A Randomized, Double-blind, Placebo-controlled Trial. Journal of Food and Nutrition Research. 2022; 10(4):305-312. doi: 10.12691/jfnr-10-4-7.

Correspondence to: Chi-Fu  Chiang, Research & Design Center, TCI CO., Ltd., Taipei, Taiwan. Email: Jimmy.Chiang@tci-bio.com

Abstract

Background: As the population ages, oral hydrolyzed collagen supplements are gaining traction. However, few clinical studies on the skin health of hydrolyzed porcine collagen combined with fish collagen. Objective: This study investigates whether TripleUp collagen beverage has skincare and anti-inflammatory effects. Methods: Using collagen beverage to treat epidermal keratinocytes and examine ROS, HA, inflammatory factor, and moisturizing-related gene expressions (Tgm1, Krt14, FLG-F, GBA, HAS3). Fifty subjects were recruited into a placebo and collagen beverage group for four weeks and then examined skin condition at 0, 2, 4 weeks. Results: TripleUp collagen beverage decreased IL-8 and ROS expression and increased moisturizing-related gene expressions. In addition, collagen beverages increase skin collagen, elasticity, moisture, and decreased spots. Conclusions: Thus, TripleUp collagen beverage included hydrolyzed porcine, and fish collagen and vitamin C can improve skin condition.

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