S. Abubakar^1,, A. B. Usman¹, I. Z. Ismaila², G. Aruwa², S. G. Azizat², G.H. Ogbadu¹, P.C. Onyenekwe¹

The work focused on the nutritional and pharmacological potential of Leptadenia hastata (pers.) Decne. ethanolic leaves extract. The proximate compositions of the leaves shows the values of moisture content (7.63 ± 0.07), Ash content (17.19 ± 0.05), Carbohydrate (47.13 ± 0.17), Crude protein (20.85 ± 0.07), Crude fibre (7.50 ± 0.05), and Crude lipid (2.70 ± 0.06). The Phytochemistry of the ethanolic leaves extract divulged the presence of Tannins, Glycosides, Alkaloids, Carbohydrates and Flavonoids. The leaves extract tested possess some decree of antimicrobial activities on Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis at 200 mg/ml and 100 mg/ml respectively. The mineral composition analysed (using Shimadzu AA 6800 Atomic Absorption Spectrophotometer) of the leaves quantified the nutritive elements such as Calcium (23.90 ± 0.01), Magnesium (147.45 ± 0.01), Sodium (1.26 ± 0.01), Iron (0.82 ± 0.00), Zinc (2.30 ± 0.05), Copper (2.86 ± 0.01), Manganese (1.80 ± 0.00), Chromium (0.25 ± 0.00) and potassium (0.18 ± 0.00). While Lead and Cadmium are absent. Nevertheless, the invitro antioxidant potentiality was evaluated using 2, 2-Diphenyl-1-Picrylhydrazyl radical (DPPH Sigma-Aldrich), which shows promising antioxidant activity of the plant leaves extract.

antibacterial, antioxidant, Elemental analysis, Leptadenia hastata, Phytochemistry, proximate composition