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Article

Assessing inflammation in obese patients using DII dietary inflammatory index – A pilot cross sectional study in Jeddah, Saudi Arabia in the year 2017

1Faculty of Applied Medical Sciences, Department of Clinical Nutrition, King Abdulaziz University, Jeddah, Saudi Arabia

2Faculty of Medicine, Department of Surgery, King Abdulaziz University, Jeddah, Saudi Arabia


Journal of Food and Nutrition Research. 2018, Vol. 6 No. 3, 137-145
DOI: 10.12691/jfnr-6-3-1
Copyright © 2018 Science and Education Publishing

Cite this paper:
Noura M S Eid, Al-Rotana Albadri, Kholoud Alshobragi, Nadin Sharqawi, Razan Albar, Abdulmalik Altaf. Assessing inflammation in obese patients using DII dietary inflammatory index – A pilot cross sectional study in Jeddah, Saudi Arabia in the year 2017. Journal of Food and Nutrition Research. 2018; 6(3):137-145. doi: 10.12691/jfnr-6-3-1.

Correspondence to: Noura  M S Eid, Faculty of Applied Medical Sciences, Department of Clinical Nutrition, King Abdulaziz University, Jeddah, Saudi Arabia. Email: ooaeid2@kau.edu.sa

Abstract

Obesity is associated with chronic low-grade inflammation caused by progressive infiltration in adipose tissue macrophage (increase M1 pro-inflammatory and decrease M2 anti-inflammatory). In this study, we aim to assess the inflammatory status of obese patients and the impact of using resveratrol as a therapeutic approach. A cross sectional trial on 10 patients from surgical word in KAUH were assessed by DII and blood test to measure there inflammatory status. In addition, a questionnaire is used to observe their social habits and medical history. Then an ex vivo study will be carried to assess the effect of resveratrol of adipose tissue macrophage. Results have shown that all volunteers had pro- inflammatory score of DII and high CRP. There was no association between types and amount of polyphenols intake and level of CRP, except flavonols was strongly associated negatively with CRP (p<0.05, R2= 0.425). DII can be used in the future as a new tool in the routine assessment of the inflammatory potential for the diet, which can be applied to obese population in Saudi Arabia. In the next step of this research, we will study the therapeutic application of resveratrol to treat obesity from inflammatory aspect.

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