Shuichi Tsubura^{1, 2,}, Kimio Uchiyama^{2, 3}, Manabu Yamada², Osamu Mimori², Shigeru Hiyama², Katsuma Katoh², Masaki Shibata²

MATATACORO^TM (containing 10 mg/l stabilized chlorine dioxide: MA-T, no alcohol, and is an odorless antibacterial agent) is useful for sterilization and disinfection. The aim of this study was to investigate whether MA-T is an appropriate mouth rinse for patients selected from whom undergoing initial periodontal treatment. The effect of rinsing with MA-T was compared with that with Concool^TM (containing 0.05% chlorhexidine gluconate: CX), Neosterine Green^TM (containing 0.02% benzethonium chloride: NG), and purified water (PW). MA-T rinsing resulted in a marked change in the BANA-score and in the VAS scale. The mean BANA scores (score ± SD) on day 0 and day 30 were 1.55±0.50 and 0.4±0.50 (p<0.001) for MA-T, 1.65±0.48 and 0.75±0.44 for CX, 1.43±0.50 and 0.88±0.61 for NG, and 1.83±0.38 and 1.48±0.55 for PW, respectively. The intra-oral feeling caused by mouth rinsing was self-assessed using the VAS scores (mean ± SD) on day 0 and day 30; they were 48.23±14.70 and 74.43±7.33 (26.2 mm increase) for MA-T, 50.45±11.94 and 62.23±8.88 (11.8 mm increase) for CX, 54.13±8.11 and 63.73±8.18 (9.6 mm increase) for NG, and 54.70±6.06 and 59.18±6.11 (4.5 mm increase) for PW, respectively. These results suggest that MA-T induced marked reduction of periodontopathic oral bacteria and increased feeling of freshness after the treatment period. These results suggest that MA-T is an appropriate mouth rinse for patient with periodontitis.

stabilized chlorine dioxide, mouth rinse, periodontitis, oral bacteria, freshness