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Trapani, G., Rheo, A. and Latrofa, A., Synthesis,1013-1014.1983.

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Article

Greener Synthesis of an Amide by Direct Reaction of an Acid and Amine under Catalytic Conditions

1Depto. de Química Orgánica, Facultad de Química, Universidad de la República (UdelaR), Montevideo, Uruguay


World Journal of Chemical Education. 2015, Vol. 3 No. 1, 27-29
DOI: 10.12691/wjce-3-1-4
Copyright © 2015 Science and Education Publishing

Cite this paper:
Gabriel Arce, Gonzalo Carrau, Ana Bellomo, David Gonzalez. Greener Synthesis of an Amide by Direct Reaction of an Acid and Amine under Catalytic Conditions. World Journal of Chemical Education. 2015; 3(1):27-29. doi: 10.12691/wjce-3-1-4.

Correspondence to: David  Gonzalez, Depto. de Química Orgánica, Facultad de Química, Universidad de la República (UdelaR), Montevideo, Uruguay. Email: davidg@fq.edu.uy

Abstract

A simple and high-yielding laboratory experiment that involves the boric acid catalyzed amidation of benzoic acid is described. The experiment makes use of recent chemistry, it is appropriate for advanced undergraduate chemistry students, and demonstrates several important concepts including homogeneous catalysis and green chemistry.

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