1Department of Biochemistry, HOD lab in-charge, Apollo Reach Hospital, Karimnagar, Andhra Pradesh
2Department of Biochemistry, Chalmeda Anadrao Institute of Medical Sciences, Karimnagar
3Department of Biochemistry, Prathima Institute of Medical Sciences, Karimnagar
American Journal of Medical and Biological Research.
2014,
Vol. 2 No. 4, 87-90
DOI: 10.12691/ajmbr-2-4-1
Copyright © 2014 Science and Education PublishingCite this paper: T Sudhakar, Sabitha Kandi, B venugopal, K. Bhagwan Reddy, K. V. Ramana. The Set Point of Intact Parathyroid Hormone-Ionized Calcium Curve during the Progression of Secondary Hyperparathyroidism among Patients Undergoing Haemodialysis.
American Journal of Medical and Biological Research. 2014; 2(4):87-90. doi: 10.12691/ajmbr-2-4-1.
Correspondence to: K. V. Ramana, Department of Biochemistry, Prathima Institute of Medical Sciences, Karimnagar. Email:
ramana_20021@rediffmail.comAbstract
The parathyroid gland secretes parathyroid hormone (PTH) which is a key element in the regulation of serum calcium. The PTH elevates serum calcium activities by regulating its action on the bones, kidneys and small intestine. The set point of PTH secretion defines the sensitivity of the parathyroid glands to calcium concentration. Secondary hyperparathyroidism (SHPT) is a common complication of end stage renal disease (ESRD). Ionized calcium is physiologically active form of calcium status of the body and is used for accurately monitoring calcium status in renal diseases. The present study states that the ionized calcium is the set point of secondary hyperparathyroidism undergoing haemodialysis and the range of set point lies between 2.3 – 4.8 mg/dl (0.57 – 1.2 mmol/L). The status of iPTH, set point are frequently monitored in subtotal hyperparathyroidectomy where imaging studies are not beneficial (anatomically situated on postero-lateral surface of thyroid gland) to know the appearance of parathyroid gland.
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