1Department of Basic Sciences, University of Lusaka, P.O Box 36711, Lusaka, Zambia
American Journal of Biomedical Research.
2024,
Vol. 12 No. 2, 11-15
DOI: 10.12691/ajbr-12-2-1
Copyright © 2024 Science and Education PublishingCite this paper: Zangini Nakazwe, Chipampe Lombe. Do Antimicrobial Resistance and Virulence Share Same Genetic Elements.
American Journal of Biomedical Research. 2024; 12(2):11-15. doi: 10.12691/ajbr-12-2-1.
Correspondence to: Zangini Nakazwe, Department of Basic Sciences, University of Lusaka, P.O Box 36711, Lusaka, Zambia. Email:
nakazwezangini@gmail.comAbstract
Antimicrobial resistance (AMR) is a growing global health challenge with increased health care costs, mortality and morbidity. Over the years, microbes of clinical importance have coevolved with their hosts and have developed virulence mechanisms through mutations and horizontal gene transfer in order to compete and withstand hash environmental conditions including those posed by antimicrobial agents. Antimicrobial resistance and virulence mechanisms promote survival of microorganisms in their hosts. Several research studies have shown putative association between antimicrobial resistance and virulence but overlooked genetic link between the two. This review focuses on establishing whether antimicrobial resistance and virulence share the same genetic elements.
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