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Koshy PJ, Sudhakar DV, Anupama SH, Mathew M, Parthasarthy R, Thangaraj K, et al. Novel homozygous FAN1 mutation in a familial case of karyomegalic interstitial nephritis. 2020; 30(4): 283.

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Article

Karyomegalic Interstitial Nephritis: Case Series and Review of Literature

1Pathology Department, Shifa International Hospital, Islamabad, 00000, Pakistan

2Nephrology Department, Shifa International Hospital, Islamabad, 00000, Pakistan


American Journal of Medical Case Reports. 2021, Vol. 9 No. 12, 693-697
DOI: 10.12691/ajmcr-9-12-8
Copyright © 2021 Science and Education Publishing

Cite this paper:
Humaira Nasir, Nida Saleem, Fatima Anwar, Rabia Saleem, Syed Nayer Mahmud. Karyomegalic Interstitial Nephritis: Case Series and Review of Literature. American Journal of Medical Case Reports. 2021; 9(12):693-697. doi: 10.12691/ajmcr-9-12-8.

Correspondence to: Nida  Saleem, Nephrology Department, Shifa International Hospital, Islamabad, 00000, Pakistan. Email: nidasaa1968@gmail.com

Abstract

Karyomegalic interstitial nephritis (KIN) is a rare cause of hereditary interstitial nephritis, described 45 years ago. Only about 50 cases have been described in English literature so far and none from Pakistan. This disease has an escalated course with a worsened outcome. There are a few potential mimickers of this disease both clinically and histologically, which might lead to a missed diagnosis and hence poor management. We have described here a series of 05 cases of KIN that were diagnosed at our institute for better understanding of this disease entity.

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