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Xu, P., Liu, X., Xiong, X., Zhang, W., Cai, X., Qiu, P., Hao, M., Wang, L., Lu, D., Zhang, X., Yang, W., “Flavonoids of Rosa roxburghii Tratt exhibit anti-apoptosis properties by regulating PARP-1/AIF”, J Cell Biochem. 118(11). 3943-3952. Nov 2017.

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Article

The Anti-Aging Activities against Oxidative Damages of Rosa roxburghii and Multi-Fruit Concentrate Drink

1Department of Dental Technology, Shu-Zen Junior College of Medicine and Management, Kaohsiung, Taiwan

2Department of Otorhinolaryngology-Head and Neck Surgery, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan

3Department of Otorhinolaryngology-Head and Neck Surgery, Kaohsiung Medical University Hospital, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

4Department of Cosmetic Science and Institute of Cosmetic Science, Chia Nan University of Pharmacy and Science, Tainan, Taiwan


Journal of Food and Nutrition Research. 2019, Vol. 7 No. 12, 845-850
DOI: 10.12691/jfnr-7-12-5
Copyright © 2019 Science and Education Publishing

Cite this paper:
Cheng Liu, Leong-Perng Chan, Chia-Hua Liang. The Anti-Aging Activities against Oxidative Damages of Rosa roxburghii and Multi-Fruit Concentrate Drink. Journal of Food and Nutrition Research. 2019; 7(12):845-850. doi: 10.12691/jfnr-7-12-5.

Correspondence to: Chia-Hua  Liang, Department of Cosmetic Science and Institute of Cosmetic Science, Chia Nan University of Pharmacy and Science, Tainan, Taiwan. Email: tinna_ling@mail.cnu.edu.tw, oleon24@yahoo.com.tw

Abstract

This research unveils potential of the Rosa roxburghii formula drink for anti-oxidation, anti-aging, anti-inflammation, and the reduction of cancer risk. We recruited 40 high risk subjects (i.e., chronic smoker or drinker) and required them to have daily supplement of R. roxburghii formula drink over 12 weeks to investigate the long-term effect on health improvement. We discovered that the drink could increase mitochondrial activity (elevated nicotinamide adenine dinucleotide (NADH) level), alleviate inflammatory response by the reduction of tumor necrosis factor alpha (TNF-α) level, and diminish the expression of cancer biomarkers of 8-hydroxy-2’-deoxyguanosine (8-OHdG) and carcinoembryonic antigen (CEA). As a result, this is the first study to elucidate the synergistic effect of R.roxburghii and other five kinds of fruits on alleviation oxidative damages.

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