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Rashtak S, Khaleghi S, Marietta EV, Pittelkow MR, Larson JJ, Lahr BD, Murray JA. Isotretinoin exposure and risk of celiac disease. PLoS One 2015; 10: 30135881.

has been cited by the following article:

Article

Isotretinoin-associated Celiac Disease

1Departments of Medicine (Gastroenterology) and Pathology, University of British Columbia, Vancouver, BC, Canada


International Journal of Celiac Disease. 2018, Vol. 6 No. 3, 89-92
DOI: 10.12691/ijcd-6-3-1
Copyright © 2019 Science and Education Publishing

Cite this paper:
Hugh James Freeman, Michael Nimmo. Isotretinoin-associated Celiac Disease. International Journal of Celiac Disease. 2018; 6(3):89-92. doi: 10.12691/ijcd-6-3-1.

Correspondence to: Hugh  James Freeman, Departments of Medicine (Gastroenterology) and Pathology, University of British Columbia, Vancouver, BC, Canada. Email: hugfree@shaw.ca

Abstract

27-yr old female marathon runner presented with profound fatigue and reduced exercise tolerance due to an iron deficiency anemia subsequent to treatment with isoretinoin for acne. Subsequent histologic and serologic studies revealed small bowel biopsies with histopathological features of celiac disease and an increased IgA tissue transglutaminase level. Isoretinoin use was terminated and after treatment with a gluten-free diet and oral iron, her symptoms resolved with normalization of her serological studies. Now, she remains completely well on a gluten-free diet alone and recently completed a full marathon.

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