1Department of Chemistry, University of the West Indies, Mona Campus, Kingston, Jamaica
World Journal of Organic Chemistry.
2016,
Vol. 4 No. 1, 13-16
DOI: 10.12691/wjoc-4-1-3
Copyright © 2016 Science and Education PublishingCite this paper: Monique N. Thompson, Winklet A. Gallimore. Constituents of the Jamaican Sponge
Iotrochota birotulata.
World Journal of Organic Chemistry. 2016; 4(1):13-16. doi: 10.12691/wjoc-4-1-3.
Correspondence to: Winklet A. Gallimore, Department of Chemistry, University of the West Indies, Mona Campus, Kingston, Jamaica. Email:
winklet.gallimore@uwimona.edu.jmAbstract
Iotrochota birotulata, an abundantly occurring sponge collected off the coast of Port Royal, Jamaica was investigated to identify its main constituents and evaluate the bioactivity associated with its crude extracts. The compounds renierapurpurin and the tyrosine derivative 1,3-dibromo-5-{2-[(p-hydroxyphenyl)-acetamido]ethyl}-2-[3-(-methyl-2-butenamido)-propoxy] benzene were isolated from the crude extract along with the common steroid β-sitosterol. The carotenoid derivative renierapurpurin was identified in this species for the first time. The structures of these compounds were elucidated using spectral analysis. When the crude extracts of the sponge were tested against the sweet potato weevil Cylas formicarius elegantulus, 100% mortality was observed at a concentration of 2 µg/mL after 72 hours.
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