A 37 years old man presented with acute ataxia and vertigo. An axial brain CT Scan without contrast showed multiple subcortical hyperdence lesions. Brain MRI with gadolinium showed multiple hyperintence lesions. Transthoracic echocardiography showed large mobile biatrial masses. Biatrial masses were resected surgically. Both tumors had the histopathological features of benign cardiac myxoma. The clinical diagnosis was multiple brain emboli from cardiac myxoma. Myxoma is a primary benign cardiac tumor with a reported incidence of 0.0017% among the general population. The patient may present with constitutional symptoms, sequelae of valvular obstruction, embolic events or sudden death. Early diagnosis and treatment of these life threatening neoplasms is the challenge for physicians. Myxomas which arise from two different cardiac chambers are uncommon.

myxoma, echocardiography, biatrial