eng Science and Education Publishing International Journal of Celiac Disease 2334-3486 2024-12-22 12 1 16 18 10.12691/ijcd-12-1-3 IJCD20241213 article Aaron Lerner 1 2 Joz¨¦lio Freire de Carvalho jotafc@gmail.com 3 Carina Benzvi 3 Chaim Sheba Medical Center, The Zabludowicz Research Center for Autoimmune Diseases, Israel N¨²cleo de Pesquisa em Doen?as Cr?nicas n?o Transmiss¨ªveis (NUPEN), School of Nutrition from the Federal University of Bahia, Salvador, Bahia, Brazil Astaxanthin, a xanthophyll carotenoid, is an abundant carotenoid in marine organisms and a very potent natural compound with remarkable anti-inflammatory and antioxidant activity. Rheumatic diseases are inflammatory conditions with excessive oxidative stress. Since non-pharmacological therapy is expanding and natural ingredients are gradually introduced to the therapeutic argumentum of rheumatic diseases, astaxanthin might be a potential candidate. A systematic review on the topic disclosed only one study with some beneficial effects on Sjogren¡¯s syndrome. Supplementation with Ast might represent a good candidate to evaluate. Further studies on Astaxanthin are highly needed. https://pubs.sciepub.com/ijcd/12/1/3/ijcd-12-1-3.pdf astaxanthin rheumatic diseases anti-inflammatory anti-oxidative