Science and Education Publishing American Journal of Public Health Research 2327-6703 3 6 2015 12 2 Prevalence of Vitamin D Deficiency and the Association between Vitamin D and Waist Circumference and the Framingham Risk Stratifications 207 213 EN Waleed S. Mohamed Internal Medicine Department, College of Medicine, Taif University, KSA Khaled Alswat AJPHR2015362 10.12691/ajphr-3-6-2 2015 8 9 2015 9 28 2015 11 30 Over the past decade, numerous non-skeletal diseases have been reported to be associated with vitamin D deficiency including coronary artery disease (CAD). CAD is a major public health problem worldwide. The aim of this study is to determine the prevalence of vitamin D deficiency and CAD among male University populations. 125 patients attending the Taif University Outpatient Clinic (TUOC) aged 20-63 years were included. Body weight, height, blood pressure, and waist circumferences (WC) were measured. Laboratory data including; total cholesterol (TC), triglycerides (TG), high and low density lipoproteins (HDL, LDL), fasting blood glucose (FBG), high sensitivity C reactive protein (CRP) and vitamin D were done. Framingham risk score (FRS) was calculated. 70.3% of the screened patients had vitamin D level < 20 ng/dl. The mean calculated FRS is 3.53. The mean age of 35.35±11.75 years, mean weight of 81.2±16.3 kg, mean body mass index (BMI) of 28.1±5.3 kg/m2, mean WC 94.9±21.5 cm, mean systolic blood pressure (SBP) of 131.6±14.2 mmHg, and mean diastolic blood pressure (DBP) of 75.8±9.9 mmHg. 7.2 % have hyperlipidemia, 6.4% have hypertension (HTN), 9.6% of the patients were type 2 diabetics (T2D) and 32.4% report family history of T2D. A significant positive correlation between FRS and age (r=0.6124), WC (r= 1998), DBP (r=0.2281), FBG (r= 0.3315), TC level (r=0.3814), TG level (r=0.4079), LDL level (r=0.2240), Non HDL level (r=0.3923) with a significant negative correlation between FRS and vitamin D level (r= -0.9473), HDL (r= -0.0091) and CRP (r= -0.0910). The overall prevalence of vitamin D insufficiency was high. There was no difference between the low and the optimal vitamin D groups. Wide screen program for early detection of vitamin D deficiency among University population both male and female and application of WC in detection of overweight/obesity and early detection of person of high CAD is recommended with application of intervention and educational programs for those at higher risk. A future wide scale study is needed to confirm our findings.