eng Science and Education Publishing American Journal of Nursing Research 2378-5586 2026-07-24 14 2 47 53 10.12691/ajnr-14-2-5 AJNR20261425 article Alaa M. Halimah 1 Ebtisam A. Elhih Elhihi.e@kamc.med.sa 2 3 Nahla A. Alzahrani 3 Hawazin Y. Alhawsaw 4 Ashwaq M. Almashi 4 Reem A. Alhassan 4 Risk Management and Patient Safety Department, King Abdullah Medical City, Makkah, Saudi Arabia Nursing Research and evidence-based practice Department, King Abdullah Medical City, Makkah, KSA Quality and Patient Safety Department, King Abdullah Medical City, Makkah, Saudi Arabia Background: Improving patient safety requires fostering a culture that encourages healthcare personnel to report errors or near miss-es without fear of punishment. This study aimed to determine the impact of patient safety culture among nurses on patient safety outcomes. Methods: A descriptive cross-sectional research design was conducted in a tertiary care hospital. An anonymous online survey method was used for data collection. It included three sections as follows: section I included nurses¡¯ demographic and work-related characteristics such as gender, marital status, level of education, section II included patient safety culture survey and section III included patient safety outcomes. The categorical variables were represented as frequency and percentage. Continuous variables were represented as mean, and standard deviation. Independent t-test was used to test the differences between two means of continuous variables. ANOVA test was used to test the differences between more than two means of continuous variables. Linear regression was conducted to test relationship between patient safety culture and various outcomes, including adverse events and self-reporting of events. Statistically significant was considered as (p-value ¡Ü 0.05 &0.01). Results: The positive response rate of patient safety culture dimensions ranged from 19.9% to 81% positive response and the overall PRR was 53.5%. It was also, observed that the majority of nurses (76.2%) rated the patient safety grade as very good/ excellent. Moreover, more than half of nurses (64.8%) never reported any event in their hospital over the past 12 months and 34.4% of the nurses reported from 1 to 5 events over the past 12 months in their hospital. There are no relationships were found among patient safety culture predictors and adverse events of falls, pressure ulcer, CLABSI and CAUTI. While a statistically significant relationship (p = 0.000) was found between patient safety culture and Self-reporting events. Conclusion: The findings indicated a need for enhancement in patient safety; thus, it is advisable to implement interventions aimed at reducing unnecessary patient harm and associated medical costs. https://pubs.sciepub.com/ajnr/14/2/5/ajnr-14-2-5.pdf Culture Outcomes Patient Safety