@article{ajn20251312,
author={{Arceo, Rebecca ¨¢lvarez and Guevara, Esteban Hern¨¢ndez and Sevilla, Judith Lerma and Garc¨ªa-Barr¨®n, Adolfo Neftal¨ª and Araiza-Verduzco, Fernanda},
title={Green Synthesis of TiO? and Ag/TiO? Nanoparticles Using <i>Rosmarinus officinalis</i> and <i>Syzygium aromaticum</i> Extracts for Potential Dental Applications},
journal={American Journal of Nanomaterials},
volume={13},
number={1},
pages={7--11},
year={2025},
url={https://pubs.sciepub.com/ajn/13/1/2},
issn={2372-3122},
abstract={Green nanotechnology provides sustainable alternatives for synthesizing functional materials with biomedical potential. This study reports the green synthesis of titanium dioxide (TiO?) and silver (Ag) nanoparticles using aqueous extracts of <i>Rosmarinus officinalis</i> (rosemary, RO) and <i>Syzygium aromaticum</i> (clove, CL) as natural reducing and stabilizing agents. UV¨CVis spectroscopy confirmed nanoparticle formation, with TiO? showing its characteristic absorption band and Ag/TiO? composites exhibiting a bathochromic shift indicative of Ag¨CTiO? interactions. Scanning electron microscopy revealed predominantly spherical nanoparticles, averaging ~165 nm for TiO? and ~96 nm for Ag deposits, while energy-dispersive spectroscopy verified elemental composition. Antibacterial assays demonstrated markedly enhanced activity of Ag/TiO? nanocomposites compared to TiO? alone, with effective inhibition against Pseudomonas aeruginosa, Staphylococcus aureus, and Escherichia coli, although lower efficacy was observed against Enterococcus faecalis. Interestingly, TiO? nanoparticles synthesized with CL extracts exhibited selective antibacterial effects, while RO-based coatings appeared to reduce antimicrobial performance. The combined bioactivity of plant-derived phytochemicals and Ag/TiO? nanostructures highlights a synergistic approach for developing biocompatible, eco-friendly antibacterial agents. These results suggest that RO- and CL-mediated Ag/TiO? nanocomposites hold promise as adjunctive materials in restorative dentistry, particularly for pulpotomy applications where antibacterial efficacy is essential.},
doi={10.12691/ajn-13-1-2}
publisher={Science and Education Publishing}
}